Results 61 to 70 of about 1,021,966 (313)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Caribbean Tertiary Education Development (1996-2006)

, 2007
The publication reflects the results of a collaboration between the Tertiary Level Institutions Unit (TLIU) of the University of the West Indies (UWI) and over 40 tertiary level institutions in the Caribbean region, focusing on the theme, “A Decade of ...
The University of the West Indies, Tertiary Levels Institutions Unit
core  

Accuracy of rapid blood coagulation testing device FibCare® in a tertiary emergency department

Acute Medicine & Surgery
Aim FibCare® is a novel point‐of‐care testing device enabling prompt evaluation of fibrinogen levels. This study aimed to investigate the accuracy of FibCare® at a tertiary emergency department.
Yutaka Mihara, Kenta Komoriya, Kei Hagiwara, Yasuhito Hatanaka, Keita Shibahashi, Mayu Hikone, Kazuhiro Sugiyama   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Comparison of Ocular Surface Squamous Neoplasia Recurrence with and Without Post-Surgical Mitomycin C 0.02% [PDF]

Journal of Liaquat National Hospital
Background: Ocular surface squamous neoplasia (OSSN) is the most common non-pigmented ocular surface tumour that presents with a high recurrence rate after surgical excision.
Hamam Barry, Zeeshan Kamil, Maham Sultan, Saeed Iqbal, Arfa Shaikh   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Media Release - Centre Director Appointed for Creative Industries - August 2009.pdf

, 2015
Media release from the Department of Innovation, Industry, Science, Research and Tertiary Education announcing the appointment of Lisa Colley as Director of the Creative Industries Innovation ...
Department of Innovation, Industry, Science, Research and Tertiary Education
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Media Release - $17M Centre to Boost Creative Industries - February 2009.pdf

, 2015
Media release from the Department of Innovation, Industry, Science, Research and Tertiary Education announcing the Creative Industries Innovation Centre, the $17M centre created to help boost the creative industries in ...
Department of Innovation, Industry, Science, Research and Tertiary Education
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source