Results 121 to 130 of about 4,958,823 (254)

DeepCARS-Identified High-Risk Patients: Clinical Interventions and Outcomes During the Korean Healthcare Crisis

Medicina
Background and Objectives: Timely recognition of deteriorating ward patients is critical to prevent adverse outcomes. The Deep learning–based Cardiac Arrest Risk Score (DeepCARS), an AI-based early warning system developed in Korea, has demonstrated high
Hyojin Jang, Wanho Yoo, Sora Hwang, Kwangha Lee   +3 more
doaj   +1 more source

Effective Factors in the Establishment and Implementation of Patient Electronic Referral System in the Healthcare System: A Qualitative Study

علوم بهداشتی ایران, 2021
Background and Purpose: The electronic referral system was established in Iran with the aim of increasing access to care, improving interaction, and efficient use of resources.
Fatemeh Tajari, Ghahraman Mahmoudi, Fatemeh Dabbaghi, Jamshid Yazdani Charati   +3 more
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Patient self-referral patterns in a developing country: characteristics, prevalence, and predictors

BMC Health Services Research
Background Efficient healthcare delivery and access to specialized care rely heavily on a well-established healthcare sector referral system. However, the referral system faces significant challenges in developing nations like Bangladesh.
Mohammad Jahid Hasan, Md. Abdur Rafi, Nahida Hannan Nishat, Ima Islam, Nusrat Afrin, Bikona Ghosh, Etminan Kabir, Samiha Zaman Akhter, Maisha Zaman Poushi, Saadi Abdullah Bin Shahnoor, Jannatul Fardous, Tamanna Tabassum, Sadia Islam, Sumiya Bent Kalam, Mehjabeen Tasnuva Aslam, Taufique Joarder   +15 more
doaj   +1 more source

Ocular morbidity, visual impairment and its association with social factors in children attending primary healthcare services for any health-related problem in Pavagada, India – A health facility-based cross-sectional study

Indian Journal of Ophthalmology
Background: Primary eye healthcare in India has potential for improvement; enhancing it can play a role in universal health coverage, integrated people-centered eye care, and reducing the burden on overloaded secondary/tertiary facilities.
Vasudha Kemmanu, Piyush V Naresh, Catey Bunce, Keerthi P Hudedagaddi, D Abhishek, G R Chandrakala, Richard Bowman, Aeesha N J Malik   +7 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Pemhigus herpetiformis: a single center tertiary care experience

Turkish Journal of Medical Sciences
Background/aim: Pemphigus herpetiformis (PH) is a rare variant of pemphigus with a complex pathogenesis that is often difficult to diagnose. The literature generally presents data based on small case series. This study aims to broaden the understanding of PH by presenting our cases’ clinical, histopathological, and immunological characteristics ...
ERKAYMAN, Merve Hatun, BİLEN, Handan, KARACA URAL, Zeynep, DEMİRCİ, Elif   +3 more
openaire   +2 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Comparison of Efficacy and Adverse Effects of 40% Hydrogen Peroxide and 50% Trichloroacetic Acid Preparations in the Treatment of Seborrheic Keratosis in A Tertiary Care Hospital

Pakistan Armed Forces Medical Journal
Objective: To compare the efficacy and adverse effects of 40% Hydrogen Peroxide versus 50% Trichloroacetic Acid in the treatment of seborrheic keratosis in a tertiary care hospital. Study Design: Quasi-experimental study. Place and Duration of Study:
Sana Zafar, Sumeera Zulfiqar, Atika Raheem, Ayesha Kanwal, Hina Mazhar, Nigah-e-Mustafa   +5 more
doaj   +1 more source