Results 91 to 100 of about 10,039 (217)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Feasibility of neurosonography in CHD-fetuses and controls in a clinical tertiary setting

European Journal of Obstetrics & Gynecology and Reproductive Biology: X
Ultrasonographic examination is the first-tier test to detect abnormal development of central nervous system (CNS). In optimal conditions, neurosonography can detect all important hallmarks of CNS development. It is, however, not known how the performance of this modality is in a routine setting.
Everwijn, S.M., Bohemen, J.F. van, Jansen, F.A., Steggerda, S.J., Teunissen, A.K., Haak, M.C.   +5 more
openaire   +4 more sources

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Factors influencing the optimal glycemic levels in type 2 diabetes mellitus patients attending the diabetic clinic of a tertiary care hospital in New Delhi

BMC Endocrine Disorders
Background Optimal glycaemic control is essential for preventing complications of type 2 diabetes mellitus (T2DM), yet a large proportion of patients fail to achieve recommended glycaemic targets even in tertiary care settings.
Ishant Kumar, Sanjeet Panesar, Rishi Kumar Jaiswal, Neelam Roy, Deepak Dhamnetiya   +4 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Aseptic technique training and infection-risk reduction practices among healthcare workers

Diversity
Healthcare-associated infections (HAIs) remain a persistent burden in resource-limited health systems, yet evidence on structured, sustained aseptic technique education for healthcare workers (HCWs) in Nigerian tertiary hospitals is still limited.
Abdulmuhit Temitope Isiaq, Seun Nurudeen Akorede, Adamu Abdulkareem Biu, Muhammad Sanusi   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

BUSINESS RISK CONTROL PRACTICES AND ENTREPRENEURIAL EDUCATION AMONG SELECTED STUDENTS IN LAGOS STATE OWNED TERTIARY INSTITUTIONS

Malete Journal of Accounting and Finance
Entrepreneurial education is core strategic development of any emerging nation whose aim is creating value addition environs for her people. Therefore, this study examines the relationship between business risk control practices and entrepreneurial ...
Oluwatoyin Frederick IDOWU, Sunday Stephen AJEMUNIGBOHUN   +1 more
doaj  

Selective Gold Precipitation by a Tertiary Diamide Driven by Thermodynamic Control

Inorganic Chemistry
The simple diamide ligand L was previously shown to selectively precipitate gold from acidic solutions typical of e-waste leach streams, with precipitation of gallium, iron, tin, and platinum possible under more forcing conditions. Herein, we report direct competition experiments to afford the order of selectivity.
Susanna S. M. Vance, Mateusz Mojsak, Luke M. M. Kinsman, Rebecca Rae, Caroline Kirk, Jason B. Love, Carole A. Morrison   +6 more
openaire   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source