Results 71 to 80 of about 407,199 (267)

Frequency of Chikungunya Virus Infection in the Tertiary Care Hospital of Karachi

Journal of Islamic International Medical College, 2021
Objective: To determine the frequency of Chikungunya virus infection in the tertiary care hospital of Karachi during the time from 1stJanuary 2017 till 31st December 2018. Study Design: This was a retrospective cross-sectional study.
Fouzia Zeeshan Khan, Fatima Fasih, Mohammad Sohaib Tauheed, Saba Hassan, Sambreen Zameer
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Research on Fuzzy Pid Control System of Temperatuer for Tertiary Air

Applied Mechanics and Materials, 2013
The introduction of the AQC boiler has complex effects on the temperature of Tertiary air, traditional PID is difficult to achieve the effective control. Combined the method of the conventional PID with the fuzzy control theory, a fuzzy self-tuning PID controller is designed.
Shaohong Jing, Junchao Zhang
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

An additional use of tertiary clarifiers: potential for ecology-based control of bacterial and genetic pollution in wastewater

npj Clean Water
Despite advancements in urban wastewater treatment, final disinfection remains the primary, yet often inefficient or costly, measure to control fecal bacteria and antibiotic resistance genes (ARGs).
Andrea Di Cesare, Raffaella Sabatino, Tomasa Sbaffi, Giulia Borgomaneiro, Diego Fontaneto, Michela Rogora, Simona Crognale, Jordi-René Mor, Laura Garzoli, Ester M. Eckert, Stefano Mammola, Arianna Orrù, Paola Giacomotti, Alejandro Martinez, Gianluca Corno   +14 more
doaj   +1 more source

Assessment of patients knowledge and attitude towards diabetes and its relationship with glycemic control: A cross-sectional study in a Nigerian tertiary hospital

Nigerian Journal of Medicine, 2019
BACKGROUND: It is postulated that increased knowledge of patients about diabetes as well as a positive attitude will lead to improved glycaemic control and better outcome.
R C Anakwue, E E Young, C C Ezenduka, C I Okoli, A N Maduforo, I D Nnakenyi, C I Ndiokwelu, O Onwujekwe   +7 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Perceived control, academic performance and well-being of Ghanaian college students with disability

African Journal of Disability, 2012
Background: Empirical evidence abounds showing the impact of perceived control on subjective well-being in several spheres of functioning, including academic performance.
Frances E. Owusu-Ansah, Peter Agyei-Baffour, Anthony Edusei   +2 more
doaj   +1 more source