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The change of entire and local tertiary protein structure about SNPs g.1884992 T>C in PAEP gene.
Yong Zhao (84950) +4 more
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Tertiary lymphoid structures in cancer
Science, 2022Tertiary lymphoid structures in cancer Tertiary lymphoid structures (TLSs) are lymphoid formations that are found in nonlymphoid tissues. TLS can develop in inflamed tissues and are associated with chronic inflammatory disorders, autoimmunity, and cancer. In the setting of tumors, TLSs facilitate the influx of immune cells into the tumor site
Ton N. Schumacher, Daniela S. Thommen
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Tertiary Structure of Ribonuclease
Nature, 1967A model is proposed of the polypeptide chain in bovine pancreatic ribonuclease based on a 2 A electron density map involving 7,294 reflexions and data from seven heavy atom derivatives. The molecule seems to be roughly kidney shaped with dimensions of about 38 × 28 × 22 A with a deep depression in the middle of one side.
G, Kartha, J, Bello, D, Harker
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Protein Tertiary Structure Prediction
Current Protocols in Protein Science, 2000AbstractThis unit addresses how to predict the tertiary structure of a protein from its amino acid sequence using computational methods. Three types of prediction methods‐‐homology modeling, fold recognition, and ab initio prediction‐‐are introduced.
D, Xu, Y, Xu
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Protein Tertiary Structure Modeling
Current Protocols in Protein Science, 2001AbstractInsights into the 3D‐structure of a protein have proven useful during experiment design. Experimentally elucidated structures are often not available, but comparative protein modeling provides a viable alternative in many cases. This unit presents comparative protein modeling and how to use the highly sophisticated but easy‐to‐use free software
Guex, N., Schwede, T., Peitsch, M. C.
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Serpin tertiary structure transformation
Journal of Molecular Biology, 1991Previous crystallographic analyses have demonstrated that proteolytic cleavage of the serpins can result in a dramatic transformation of their tertiary structure. Some 16 residues on the amino terminal side of the cleavage site are inserted into a large beta-sheet to become a central strand, separating the two cleaved residues by about 70 A.
P, Stein, C, Chothia
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Calculation of protein tertiary structure
Journal of Molecular Biology, 1976Abstract We describe a method for calculating the tertiary structure of proteins given their amino acid sequence. The algorithm involves locally minimizing an energylike expression as a function of the Cartesian co-ordinates of the C β of all residues.
I D, Kuntz +3 more
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