Results 291 to 300 of about 798,978 (348)

The change of entire and local tertiary protein structure about SNPs g.1884992 T>C in PAEP gene.

open access: green
Yong Zhao (84950)   +4 more
openalex   +1 more source

Co-existence atlas of immune cell types in tertiary lymphoid structures (TLSs) region of renal cell carcinoma (RCC) patients.

open access: green
Huamei Li (8815955)   +9 more
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Tertiary lymphoid structures in cancer

Science, 2022
Tertiary lymphoid structures in cancer Tertiary lymphoid structures (TLSs) are lymphoid formations that are found in nonlymphoid tissues. TLS can develop in inflamed tissues and are associated with chronic inflammatory disorders, autoimmunity, and cancer. In the setting of tumors, TLSs facilitate the influx of immune cells into the tumor site
Ton N. Schumacher, Daniela S. Thommen
openaire   +4 more sources

Tertiary Structure of Ribonuclease

Nature, 1967
A model is proposed of the polypeptide chain in bovine pancreatic ribonuclease based on a 2 A electron density map involving 7,294 reflexions and data from seven heavy atom derivatives. The molecule seems to be roughly kidney shaped with dimensions of about 38 × 28 × 22 A with a deep depression in the middle of one side.
G, Kartha, J, Bello, D, Harker
openaire   +4 more sources

Protein Tertiary Structure Prediction

Current Protocols in Protein Science, 2000
AbstractThis unit addresses how to predict the tertiary structure of a protein from its amino acid sequence using computational methods. Three types of prediction methods‐‐homology modeling, fold recognition, and ab initio prediction‐‐are introduced.
D, Xu, Y, Xu
openaire   +2 more sources

Protein Tertiary Structure Modeling

Current Protocols in Protein Science, 2001
AbstractInsights into the 3D‐structure of a protein have proven useful during experiment design. Experimentally elucidated structures are often not available, but comparative protein modeling provides a viable alternative in many cases. This unit presents comparative protein modeling and how to use the highly sophisticated but easy‐to‐use free software
Guex, N., Schwede, T., Peitsch, M. C.
openaire   +2 more sources

Serpin tertiary structure transformation

Journal of Molecular Biology, 1991
Previous crystallographic analyses have demonstrated that proteolytic cleavage of the serpins can result in a dramatic transformation of their tertiary structure. Some 16 residues on the amino terminal side of the cleavage site are inserted into a large beta-sheet to become a central strand, separating the two cleaved residues by about 70 A.
P, Stein, C, Chothia
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Calculation of protein tertiary structure

Journal of Molecular Biology, 1976
Abstract We describe a method for calculating the tertiary structure of proteins given their amino acid sequence. The algorithm involves locally minimizing an energylike expression as a function of the Cartesian co-ordinates of the C β of all residues.
I D, Kuntz   +3 more
openaire   +2 more sources

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