Results 91 to 100 of about 12,489 (231)

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Multiplex visual nucleic acid detection via isothermal cascaded transcription of fluorescent RNA aptamers

VIEW, EarlyView.
(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang, Na Luo, Binbin Xie, Jie Luo, Yaling Yuan, Junjie Fan, Zhiyong Liu, Haiyan Gao, Ming Chen, Kai Chang   +9 more
wiley   +1 more source

DreamTel; Diabetes risk evaluation and management tele-monitoring study protocol [PDF]

, 2009
Background The rising prevalence of type 2 diabetes underlines the importance of secondary strategies for the prevention of target organ damage. While access to diabetes education centers and diabetes intensification management has been shown to improve ...
Sheldon W Tobe, Joan Wentworth, Laurie Ironstand, Susan Hartman, Jackie Hoppe, Judi Whiting, Janice Kennedy, Colin McAllister, Alex Kiss, Nancy Perkins, Lloyd Vincent, George Pylypchuk, Richard Z Lewanczuk, LL Lipscombe, RR Holman, A Patel, HC Gerstein, SW Tobe, EH Wagner, BJ Manns, WE Hoy, RF Dyck, RF Dyck, MP Pioro, TK Young, B Muneta, N Morrison, W Hoy, G Pylypchuk, ML Sievers, SS Anand, BV Howard, JL Ellis, RB Devereux, BV Howard, W Hoy, D Campos-Outcalt, TK Welty, BV Howard, BV Howard, LM Ruilope, HC Gerstein, JF Mann, JA London, J Gittelsohn, YD Roubideaux, M Daniel, KG Rowley, D Gohdes, The Diabetes Control and Complication (DCCT) Research Group, P Gaede, BTC Indian Health Services, G Pylypchuk, PL Hoskins, AD Harrower, SE Nissen, OCAP, SR Weingarten, AM Kriska, BR Shah, RE Aubert, J Menard, J Hintze   +62 more
core   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

Are patients with high-risk polycythemia vera receiving cytoreductive medications? A retrospective analysis of real-world data

Experimental Hematology & Oncology, 2018
Background Patients with polycythemia vera (PV) have a higher mortality risk compared with the general population, primarily driven by cardiovascular disease, thrombotic events (TEs), and hematologic transformations.
Dilan Paranagama, Philomena Colucci, Kristin A. Evans, Machaon Bonafede, Shreekant Parasuraman   +4 more
doaj   +1 more source

Prediction of Minimally Conscious State Responder Patients to Non-invasive Brain Stimulation Using Machine Learning Algorithms

, 2021
peer reviewedThe right matching of patients to an intended treatment is routinely performed by doctor and physicians in healthcare. Improving doctor’s ability to choose the right treatment can greatly speed up patient’s recovery.
Andrés Rojas, Eleni Kroupi, Géraldine Martens, Aurore Thibaut, Alice Barra, Steven Laureys, Giulio Ruffini, Aureli Soria-Frisch   +7 more
core   +1 more source

The oscillatory response of the electroretinogram and neuronal adaptation

Acta Ophthalmologica, EarlyView.
Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley   +1 more source

Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells

Brain Pathology, EarlyView.
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son, Suji Kim, Min‐Tae Jeon, Moonseok Choi, Kyu‐Sung Kim, Suji Lee, Seung‐Yeol Nah, Do‐Geun Kim   +7 more
wiley   +1 more source

Supportive Periodontal Therapy Improves Implant Survival in Patients With a History of Periodontitis: A Retrospective Multicenter Cohort Study of 3555 Implants

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objective This study evaluated the 5‐year survival of bone‐level, internal connection, sandblasted and acid‐etched (SA) implants and identified site‐ and patient‐related risk factors for implant failure in a multicenter cohort. Materials and Methods A total of 3555 tapered bone‐level SA implants were placed between 2012 and 2018 at two ...
Dongseob Lee, Sungrak Ahn, Jin Young Park, Seung‐Ju Lee, Yong‐Moo Lee, Ki‐Tae Koo, Hyung Jin Lee, Shin Kyu Lee, Ji‐Young Joo, Jungwon Lee   +9 more
wiley   +1 more source

Adiponectin as the main representative of adipokines: role in pathology, possibilities of TES-therapy

Medical news of the North Caucasus, 2022
Sergey Aleksandrovich Zanin, Elena Alekseevna Chabanets, Azamat Kade, Pavel Pavlovich Polyakov, Artem Ivanovich Trofimenko, Ekaterina Sergeevna Zanina   +5 more
openaire   +1 more source