Results 11 to 20 of about 5,930,377 (260)

Comparing molecular and computational approaches for detecting viral integration of AAV gene therapy constructs

open access: yesMolecular Therapy: Methods & Clinical Development, 2023
Many current gene therapy targets use recombinant adeno-associated virus (AAV). The majority of delivered AAV therapeutics persist as episomes, separate from host DNA, yet some viral DNA can integrate into host DNA in different proportions and at genomic
Elias M. Oziolor   +8 more
doaj   +2 more sources

Recurrent giant cell tumour of the thoracic spine managed by total en bloc spondylectomy and denosumab therapy: a case report

open access: yesBMC Musculoskeletal Disorders, 2020
Background Giant cell tumour (GCT) of the bone is a rare, invasive benign bone tumour, which typically originates in the metaphyseal ends of long bones and rarely in the spine.
Ping-Guo Duan   +4 more
doaj   +2 more sources

Adiponectin as the main representative of adipokines: role in pathology, possibilities of TES-therapy

open access: yesMedical news of the North Caucasus, 2022
Sergey Aleksandrovich Zanin   +5 more
openaire   +2 more sources

Outcomes of transcorneal electrical stimulation therapy in the early stages of retinitis pigmentosa

open access: yesTurkish Journal of Medical Sciences, 2022
Background/aim: To investigate the effect of transcorneal electrical stimulation (TES) therapy in patients with retinitis pigmentosa (RP). Materials and methods: We performed TES therapy in 21 patients with RP in 12 sessions with 1-week intervals.
Acar, Ugur   +3 more
core   +2 more sources

PARAMETRIC VARIATION OF MICROCIRCULATION AFFECTED BY TES-THERAPY

open access: yesThe Bulletin of Contemporary Clinical Medicine, 2018
Aim. The effect of TES-therapy on the condition of microcirculatory blood flow was studied in patients with somatic comorbid diseases – chronic obstructive pulmonary disease (COPD) and systemic arterial hypertension (AH). Material and methods.
ELENA G. ZARUBINA   +2 more
openaire   +2 more sources

Novel Non-invasive Transcranial Electrical Stimulation for Parkinson’s Disease

open access: yesFrontiers in Aging Neuroscience, 2022
Conventional transcranial electrical stimulation (tES) is a non-invasive method to modulate brain activity and has been extensively used in the treatment of Parkinson’s disease (PD).
Rui Ni   +14 more
doaj   +1 more source

RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer

open access: yesCell Reports, 2023
SUMMARY Tumors with mutations in chromatin regulators present attractive targets for DNA hypomethylating agent 5-aza-2′-deoxycytidine (DAC) therapy, which further disrupts cancer cells’ epigenomic fidelity and reactivates transposable element (TE ...
Hong-Tao Li   +13 more
semanticscholar   +1 more source

2021 global lung cancer therapy landscape.

open access: yesJournal of Thoracic Oncology, 2022
BACKGROUND The lung cancer treatment landscape has significantly evolved over the past decade. However, a systematic analysis of the current global drug development landscape has not been conducted.
D. Deb, A. Moore, U. Roy
semanticscholar   +1 more source

Influence of segmentation accuracy in structural MR head scans on electric field computation for TMS and tES [PDF]

open access: yesPhysics in Medicine and Biology, 2020
In several diagnosis and therapy procedures based on electrostimulation effect, the internal physical quantity related to the stimulation is the induced electric field. To estimate the induced electric field in an individual human model, the segmentation
E. Rashed, J. Gómez-Tames, A. Hirata
semanticscholar   +1 more source

Using transcranial magnetic therapy in combination with electrostimulation for correcting neuroendocrine-immune disorders in obese boys

open access: yesRussian Open Medical Journal, 2022
Objective — To justify the use of low-intensity transcranial magnetic therapy (TCMT) in combination with electrostimulation (TES) for the correction of neuroendocrine-immune disorders.
Nina V. Bolotova   +5 more
doaj   +1 more source

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