Results 71 to 80 of about 12,337 (202)

The Holy Grail of Tissue Engineering? Islet Cell Microencapsulation in Type 1 Diabetes Mellitus [PDF]

, 2015
The immunoisolation of transplanted islet cells represents a promising future therapy for the treatment of type 1 diabetes mellitus (T1DM). Microencapsulation is one avenue being explored to restore insulin independence while simultaneously protecting ...
Woods, Brian
core   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

DYNAMICS CYTOKIN'S OF THE STATUS AT PATIENTS WITH THE ISOLATED CRANIOCEREBERAL TRAUMA OF AVERAGE AND HEAVY SEVERITY LEVEL

Кубанский научный медицинский вестник, 2014
In work the estimation cytokin’s the status (IL-1 β, IL -4, IL -6, IL -10) at patients with CCT average and heavy severity level is spent. All patients have been divided into 2 groups: 1 (n=25) - therapy CCT under the report and 2 (n=25) - therapy CCT ...
E. E. Bajkova, A. Kh. Kade, G. G. Muzlaev, V. P. Lebedev, S. A. Zanin   +4 more
doaj  

CARDIOVASCULAR SAFETY IN THERAPY OF DIABETES MELLITUS TYPE 2

Медицинский совет, 2016
Diabe tes mellitus is chronical disease, lead to vascular complications. The safety of hypoglycemic therapy influences on cardiovascular complications.
A. F. VERBOVOY, A. V. PASHENTSEVA, Y. A. DOLGIKH, A. S. OSINA, L. A. SHARONOVA   +4 more
doaj   +1 more source

Anionic Liposomes as Optimal Membrane Fusion Carriers Enabling in Situ Multiplexed Detection of Extracellular Vesicle MicroRNAs

Advanced Science, EarlyView.
A novel strategy for in situ multiplexed miRNA analysis of plasma extracellular vesicles (EValarm) has been developed. EValarm enables straightforward detection of different extracellular vesicle miRNAs from plasma samples through systematic screening of liposome surface charges, without requiring complex pretreatment steps, and achieves satisfactory ...
Jing‐Yuan Ma, Xiao Wang, Yuhan Cai, Guancheng Wang, Mingze Lu, Kaizheng Feng, Ying Zhao, Xue Wu, Xiaoping Zhang, Haoan Wu, Wei Yu, Ming Ma, Zheng Ge, Yu Zhang   +13 more
wiley   +1 more source

DreamTel; Diabetes risk evaluation and management tele-monitoring study protocol [PDF]

, 2009
Background The rising prevalence of type 2 diabetes underlines the importance of secondary strategies for the prevention of target organ damage. While access to diabetes education centers and diabetes intensification management has been shown to improve ...
A Patel, AD Harrower, Alex Kiss, AM Kriska, B Muneta, BJ Manns, BR Shah, BTC Indian Health Services, BV Howard, BV Howard, BV Howard, BV Howard, Colin McAllister, D Campos-Outcalt, D Gohdes, EH Wagner, G Pylypchuk, G Pylypchuk, George Pylypchuk, HC Gerstein, HC Gerstein, J Gittelsohn, J Hintze, J Menard, JA London, Jackie Hoppe, Janice Kennedy, JF Mann, JL Ellis, Joan Wentworth, Judi Whiting, KG Rowley, Laurie Ironstand, LL Lipscombe, Lloyd Vincent, LM Ruilope, M Daniel, ML Sievers, MP Pioro, N Morrison, Nancy Perkins, OCAP, P Gaede, PL Hoskins, RB Devereux, RE Aubert, RF Dyck, RF Dyck, Richard Z Lewanczuk, RR Holman, SE Nissen, Sheldon W Tobe, SR Weingarten, SS Anand, Susan Hartman, SW Tobe, The Diabetes Control and Complication (DCCT) Research Group, TK Welty, TK Young, W Hoy, W Hoy, WE Hoy, YD Roubideaux   +62 more
core   +3 more sources

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Результати дослідження стресових реакцій у хворих із поєднаною травмою середньої зони обличчя після застосування комплексної післяопераційної реабілітації [PDF]

, 2020
Summary. The frequency of the midface bone demages area occupy the second place among the all maxillo-facial fractures. In all cases, these injuries are accompanied by multiple, often multi-fragmented fractures of zygomatic-orbital complex.
Ilnytskyi, Ya. M., Melnychuk, Yu. M., Nazarevych, M. R., Ohonovskyi, R. Z., Pohranychna, Kh. R.   +4 more
core   +2 more sources

Surgical Outcomes and Recurrence Management in Borderline Resectable Hepatocellular Carcinoma: Implications for Multidisciplinary Strategies

Annals of Gastroenterological Surgery, EarlyView.
Multivariate analysis identified that up‐to‐7 out (p < 0.001), lymph node metastasis (p < 0.001), and non‐anatomical resection (p = 0.02) were independent predictors of cancer recurrence, while older age (p = 0.01), Child‐Pugh B (p < 0.001), up‐to‐7 out (p = 0.01), macrovascular invasion (p = 0.01), and lymph node metastasis (p < 0.001) were ...
Koichiro Haruki, Kenei Furukawa, Munetoshi Akaoka, Yuto Yamahata, Shinji Onda, Yoshihiro Shirai, Masashi Tsunematsu, Tomohiko Taniai, Michinori Matsumoto, Toru Ikegami   +9 more
wiley   +1 more source

Closing the policy gap in diabetes care for individuals with advanced CKD [PDF]

Aim: The co-existence of diabetes and CKD poses significant challenges to healthcare systems, current frameworks often inadequately address the complex needs of individuals with both conditions.
Habte-Asres, Hellena Hailu, Nitsch, Dorothea, Rosenthal, Miranda, Wheeler, David C   +3 more
core   +4 more sources