Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Manufacturing and high heat flux testing of advanced target mock-ups for the EU-DEMO divertor target
Among the R&D tasks undertaken for the technological development of plasma facing components, a research activity has been undertaken under the framework of the EUROfusion consortium to pursue the consolidation and verification of the current target ...
P. Lorusso +14 more
doaj +1 more source
Anti‐Allergic Potential of Chamaecrista nomame and Its Compound Luteolin for Novel Asthma Therapy
Chamaecrista nomame (CN) and its active compound luteolin attenuate allergic airway inflammation by inhibiting mast cell activation and suppressing NF‐κB/MAPK signaling, leading to reduced cytokine production and OVA‐specific IgE levels. ABSTRACT Asthma is a chronic inflammatory disease driven by dysregulated immune responses and mast cell activation ...
Tae Kyeom Kang +8 more
wiley +1 more source
Investigation of Hf/Ti bilayers for the development of transition-edge sensor microcalorimeters
The superconducting properties of 85 nm thick hafnium thin films with a 5 nm thick titanium layer on top have been investigated for three different geometries, that is, a film covering the entire 7 × 7 mm2 chip surface, bridges with a width of 200 μm and
Victoria Y. Safonova +5 more
doaj +1 more source
Ko Te Mouri O Te Mahi Te Mouri O Te Ora
Tonga Karena +2 more
openaire +1 more source
Epx4 Nanopore With Multiple Constrictions for Single‐Molecule Identification
Epx4 is a biological multi‐constriction nanopore that generates informative current signals for polypeptide sensing. Compared with α‐hemolysin, Epx4 detects short poly‐L‐lysine (S‐PLL, Mw 10 kDa) at a higher event frequency and produces signal features that distinguish it from long poly‐L‐lysine (L‐PLL, Mw 30–70 kDa), with an ROC AUC of 0.82 for the ...
Ayako Ijuin +7 more
wiley +1 more source
VIOLENCIA DE GÉNERO EN LA PAREJA CONTRA MUJERES INMIGRANTES: UN ESTADO DEL ARTE
Este artículo presenta una revisión de la literatura acerca de la violencia de género en la pareja en comunidades inmigrantes. Para ello, se busca establecer puntos de encuentro y divergencia entre los estudios realizados en España sobre la temática y ...
Roberta de Alencar Rodrigues +2 more
doaj
rDNAmine: A New Tool for the Analysis of Long Repetitive Sequences
This work introduces a novel approach for analysing long repetitive genomic sequences, combining a method to isolate large DNA molecules from individual chromosomes. We also describe the bioinformatics tool rDNAmine, which enables the isolation of long‐repeat sequences from reads obtained using the Oxford Nanopore method, as well as their preliminary ...
Agnieszka Czarnocka‐Cieciura +1 more
wiley +1 more source
The Effect of Variable Na/K on the CO2 Content of Slab‐Derived Rhyolitic Melts
This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Michelle Muth +2 more
wiley +1 more source
Abstract Remarkably little is known about what factors drive success or failure in foreign policy. In part, this is because there is little fundamental agreement on what constitutes success or failure in this domain in the first place. This article engages with these shortcomings by comparing two similar regional order‐building initiatives overseen by ...
Benjamin Day
wiley +1 more source

