Results 91 to 100 of about 596,923 (301)

Automation of electromagnetic compatability (EMC) test facilities [PDF]

Efforts to automate electromagnetic compatibility (EMC) test facilities at Marshall Space Flight Center are discussed. The present facility is used to accomplish a battery of nine standard tests (with limited variations) deigned to certify EMC of Shuttle
Harrison, C. A.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Toward Fully-Automated Hardware-in-the-Loop Grid Code Compliance Certification of Inverter-Based Distributed Energy Resources

IEEE Access
Inverter-based Distributed Energy Resources (DERs) third-party compliance testing has been widely required by most grid codes to guarantee interoperability with the electrical power system. However, most grid code certification procedures only accept the
Luiz Fernando Rissotto Menegazzo, Anderson Luis do Nascimento Severo, Ricardo Jochann Franceschi Bortolini, Lucas Biselo Piton, Henrique Magnago, Fernanda de Morais Carnielutti, Lucas Vizzotto Bellinaso, Leandro Michels, Humberto Pinheiro   +8 more
doaj   +1 more source

Maintenance of Automated Test Suites in Industry: An Empirical study on Visual GUI Testing

, 2016
Context: Verification and validation (V&V) activities make up 20 to 50 percent of the total development costs of a software system in practice. Test automation is proposed to lower these V&V costs but available research only provides limited empirical ...
Alégroth, Emil, Feldt, Robert, Kolström, Pirjo   +2 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A Secure Scheme for Distributed Consensus Estimation against Data Falsification in Heterogeneous Wireless Sensor Networks

Sensors, 2016
Heterogeneous wireless sensor networks (HWSNs) can achieve more tasks and prolong the network lifetime. However, they are vulnerable to attacks from the environment or malicious nodes.
Shichao Mi, Hui Han, Cailian Chen, Jian Yan, Xinping Guan   +4 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

AUnit - a testing framework for alloy [PDF]

, 2014
textWriting declarative models of software designs and analyzing them to detect defects is an effective methodology for developing more dependable software systems.
Sullivan, Allison
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source