Results 51 to 60 of about 596,923 (301)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Voltage Flicker Detection Based on Probability Resampling

Energies, 2020
Digital flicker detection devices need to store a large amount of evaluation data during measurement process, which leads to high requirements for hardware resources and algorithm execution efficiency.
Haitao Gao, Peng Xu, Jin Tao, Shihui Huang, Rugang Wang, Quan Zhou   +5 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

3D Face Authentication Software Test Automation

IEEE Access, 2020
The 3D face authentication has become a hot trend for researchers and developers in the recent years, due to its many advantages over the 2D face recognition feature.
Debdeep Banerjee, Kevin Yu
doaj   +1 more source

Automated Functional Testing based on the Navigation of Web Applications

, 2011
Web applications are becoming more and more complex. Testing such applications is an intricate hard and time-consuming activity. Therefore, testing is often poorly performed or skipped by practitioners.
Dueñas, Juan Carlos, García, Boni
core   +2 more sources

Non-parametric comparison of histogrammed two-dimensional data distributions using the Energy Test [PDF]

, 2012
When monitoring complex experiments, comparison is often made between regularly acquired histograms of data and reference histograms which represent the ideal state of the equipment.
, Aslan B, Aslan B, Chakravati I M, Devroye L, Gaboune B, Ivan D Reid, Lopes R H C, Peacock J A, Peter R Hobson, Raul H C Lopes, Reid I D, Weisstein E W, Zech G   +13 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

6G DevOps: Facilitating AI and Yielding Systematic Insights in 6G Evolution

IEEE Access
The increasing complexity of 6G networks, driven by advanced techniques such as virtualization, AI/ML integration, and disaggregated architectures, creates unprecedented challenges for testing and validating network functions before deployment ...
Francisco J. Garcia, Haoxin Sun, Mattia Lecci, Javier Rivas, German Corrales Madueno, Francisco Muro, Francisco Crespo, Hao Qiang Luo-Chen, Carlos S. Alvarez-Merino, David Segura, Emil J. Khatib, Sergio Fortes, Raquel Barco   +12 more
doaj   +1 more source

Human-automation collaboration in manufacturing: identifying key implementation factors [PDF]

, 2013
Human-automation collaboration refers to the concept of human operators and intelligent automation working together interactively within the same workspace without conventional physical separation.
Charalambous, George, Fletcher, Sarah R., Webb, Philip   +2 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source