Results 91 to 100 of about 17,805,684 (388)

Chemistry for Covalent Modification of Endogenous/Native Proteins: From Test Tubes to Complex Biological Systems.

open access: yesJournal of the American Chemical Society, 2019
Chemical modification of proteins provides powerful tools to realize a broad range of exciting biological applications, including the development of new classes of biopharmaceuticals and functional studies of individual proteins in complex biological ...
Tomonori Tamura, I. Hamachi
semanticscholar   +1 more source

Using exoplanets to test the universality of biology [PDF]

open access: yesNature Astronomy, 2018
The detection of biosignatures on extrasolar planets would allow us to explore the predictability of evolution. What could we learn without directly obtaining a sample of life?
openaire   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Ecological mechanisms of microbial assembly in clonal plant Glechoma longituba: from soil to endosphere

open access: yesApplied and Environmental Microbiology
Climate change presents significant challenges to plant growth and reproduction. Clonal plants, with low genetic diversity, are particularly vulnerable due to their limited adaptive capacity.
Yunshi Li   +4 more
doaj   +1 more source

Analisis Profil Alat Evaluasi Siswa Buatan Guru Biologi [PDF]

open access: yes, 2014
This research aimed to know profile student evaluation instrument made by certified teacher of biology in state high school at Madiun regency. Population and sample were teachers of biology as many 18 teachers.
KURNIAWATI, S. J. (SUKMA)
core   +1 more source

A unified design space of synthetic stripe-forming networks [PDF]

open access: yes, 2014
Synthetic biology is a promising tool to study the function and properties of gene regulatory networks. Gene circuits with predefined behaviours have been successfully built and modelled, but largely on a case-by-case basis.
Cotterell, J   +5 more
core   +3 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Undergraduate Students’ Mental Model of Cell Biology

open access: yesJurnal Pendidikan IPA Indonesia, 2017
A descriptive study of future teacher students’ mental models of essential concepts in Cell Biology was carried out through explanatory mixed-methods.
S. Saptono, W. Isnaeni, S. Sukaesih
doaj   +1 more source

BioBits™ Bright: A fluorescent synthetic biology education kit

open access: yesScience Advances, 2018
We report portable, user-friendly reagents and equipment for visual, hands-on biology activities with supporting curriculum. Synthetic biology offers opportunities for experiential educational activities at the intersection of the life sciences ...
Jessica C. Stark   +39 more
semanticscholar   +1 more source

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