Results 71 to 80 of about 1,730,969 (264)

Analysis of the lipid-lowering activity and mechanism of Betukladin based on a zebrafish model [PDF]

open access: yesShandong kexue
Betukladin is a dietary supplement composed of reindeer lichen powder and birch bark extract, possessing various pharmacological activities such as blood glucose regulation, lipid lowering, anti-inflammatory effects, and anticoagulation.
DU Xingshuo, ZHAN Wen, GAO Songying, SUN Changgao, XU Mingxian, ZHANG Sichen, LI Hongliang, XIA Qing, HE Qiuxia
doaj   +1 more source

TESTING FOR EVOLUTIONARY RELATIONSHIP: AN APPLICATION OF MATHEMATICS IN MOLECULAR BIOLOGY [PDF]

open access: yesCOSMOS, 2005
The paper illustrates some mathematical problems that are motivated by molecular biological applications and the techniques that are used to address them. The context is that of detecting evolutionary relationship on the basis of molecular sequence data and of measuring its strength.
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Undergraduate Students’ Mental Model of Cell Biology

open access: yesJurnal Pendidikan IPA Indonesia, 2017
A descriptive study of future teacher students’ mental models of essential concepts in Cell Biology was carried out through explanatory mixed-methods.
S. Saptono, W. Isnaeni, S. Sukaesih
doaj   +1 more source

Diagnostic value of phenotypic testing combined with molecular biology testing for tuberculosis

open access: yesScientific Reports
Abstract To evaluate the diagnostic value of combining phenotypic testing with molecular biology testing for tuberculosis, a retrospective study was conducted on 264 presumed pulmonary tuberculosis patients across four hospitals from July 2021 to September 2023.
Wang, Xianlei   +6 more
openaire   +3 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

The Thing about Chemistry: Investigating the Fundamental Chemistry Skills of Biology Education Students at Bielefeld University

open access: yesScience Education International, 2019
Although fundamental chemistry acts as a prerequisite for fully comprehending imperative aspects of biology, Bielefeld University is one of three universities in North Rhine-Westphalia, Germany that does not require majors or minors in biology education ...
Claas Wegner   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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