Results 51 to 60 of about 1,730,969 (264)

Extended time on an unspeeded assessment improves neither test anxiety nor performance

Frontiers in Education
IntroductionThe amount of time students are given to complete an assessment is a pragmatic element to the assessment itself. Assessments that provide the vast majority (>80%) of students sufficient time for completion are said to be “unspeeded ...
Nicole Marcus, Liam O'Connor Mueller, James E. Cooke   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Functional divergence of BnaWRKY7 homologs drives phytosterol variations in polyploid Brassica napus

Journal of Advanced Research
Introduction: Gene duplication and subsequent functional divergence drive species evolution, adaptability, and biodiversity, particularly in polyploids.
Xueyan Wang, Xuan Tian, Xiong Zhang, Yizhou He, Qinglin Ke, Li Yu, Fei Ma, Xuefang Wang, Shengyi Liu, Yuanyuan Zhang, Liangxiao Zhang, Peiwu Li   +11 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

PENGUJIAN VALIDITAS DAN PRAKTIKALITAS TES DISPOSISI BERPIKIR KRITIS DALAM BIOLOGI (TDBKB)

Jurnal Pendidikan Sains Universitas Muhammadiyah Semarang, 2019
Good instruments are not only seen from validity and reliability but can also be seen from practical values. The purpose of this study is to examine content validity and practicality of critical thinking disposition tests in biology.
Jayanti Syahfitri
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Geographical Variation in Nutritional Components of Peanut: Evidence From Multi‐Region Production Areas

Food Frontiers
As an important oilseed and food material, the nutritional quality of peanut is influenced by not only the variety but also place of origin. However, research on the geographical impact remains scarce. In this study, nine peanut cultivars were planted at
Xueyan Wang, Xin Qi, Xiaofeng Yue, Mengxue Fang, Ao Liu, Fei Ma, Li Yu, Xuefang Wang, Du Wang, Peiwu Li, Liangxiao Zhang   +10 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source