Results 51 to 60 of about 1,766,427 (312)

An In-House Biology Placement Test Improves Success in Majors Introductory Biology [PDF]

open access: yesThe American Biology Teacher, 2017
Biology placement tests (BPTs) have most often been used to determine whether well-prepared students can “test out” of foundational coursework at the college or university level. However, not all high school students are equally prepared for majors-level introductory Biology.
Jesse P. Poole   +4 more
openaire   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Genetic Testing in the Diagnosis and Biology of Acute Leukemia

open access: yesAmerican Journal of Clinical Pathology, 2019
AbstractObjectivesThe 2017 Workshop of the Society for Hematopathology/European Association for Haematopathology examined the role of molecular genetics in the diagnosis and biology of acute leukemia.MethodsAcute leukemias were reviewed in two sessions: “Genetic Testing in Diagnosis of Acute Leukemias” (53 cases) and “Genetics Revealing the Biology of ...
Marian H, Harris   +3 more
openaire   +2 more sources

Integrated bioinformatics analysis reveals Netrin-1 as a key molecular link between Parkinson’s disease and heart failure

open access: yesFrontiers in Aging Neuroscience
BackgroundParkinson’s disease (PD) patients face a higher risk of developing heart failure (HF). The objective of the study was to investigate the hub genes and potential mechanisms linking Parkinson’s disease (PD) to heart failure (HF) using multiple ...
Zhen Ni   +10 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Dynamic changes and early warning of peanuts aflatoxin B1 contamination in China in the context of climate change

open access: yesnpj Science of Food
Aflatoxin contamination is a major food safety concern and has a particularly negative impact on peanuts. Climate conditions are known to influence the natural occurrence of mycotoxins; however, the specific impacts of climate change on the prevalence of
Can Guo   +12 more
doaj   +1 more source

Evaluation of the antioxidant and anti-inflammatory efficacy of fermented Polygonatum sibiricum using zebrafish model

open access: yesBiochemistry and Biophysics Reports
Background: Fermentation may enhance the skincare potential of the traditional Chinese medicine Polygonatum sibiricum (PS). This study aimed to evaluate the anti-oxidant and anti-inflammatory efficacy of fermented Polygonatum sibiricum (FPS) using ...
Wenjuan Cao   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Metabolome and transcriptome analysis reveal the effect of methyl jasmonate on phytosterol biosynthesis in Brassica napus

open access: yesFood Frontiers
Phytosterols are a group of nonpharmacological alternatives to prevent or control dyslipidemias and cardiovascular disease. Increasing the phytosterol content in rapeseed oil is important to enhance daily phytosterol intake.
Xueyan Wang   +13 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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