Results 191 to 200 of about 17,620,834 (388)

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Synthetic DNA Synthesis and Assembly: Putting the Synthetic in Synthetic Biology.

open access: yesCold Spring Harbor Perspectives in Biology, 2017
R. Hughes, A. Ellington
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Evaluation protocols for the extraction of genomic DNA from Bovine blood

open access: yesJournal of the Selva Andina Research Society, 2016
Basic studies on DNA extraction techniques are very important for the success of scientific papers in the field of molecular biology. The extraction and purification of nucleic acids are critical steps for establishing further genetic analysis.
Crispim Bruno do Amaral   +6 more
doaj  

Biology and Clinical Implications of Fecal Occult Blood Test Screen-Detected Colorectal Cancer

open access: green, 2022
Shehara Mendis   +14 more
openalex   +2 more sources

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