Results 171 to 180 of about 1,766,427 (312)

TCRBinder: Unified pre-trained language model with paired-chain synergy for predicting T-cell receptor binding specificity. [PDF]

PLoS Comput Biol
Dong W, Yang Q, Xu L, Li X, Wang K, Dong S, Luo G, Zhang X, Yang T, Gao X, Wang G.   +10 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Host Plant Preferences and Survival of the Native Australian Spittlebug, <i>Bathyllus albicinctus</i> Erichson (Hemiptera: Cercopoidea). [PDF]

Biology (Basel)
Jaroslow D, Nancarrow N, Blacket M, Selleck C, Mavende KP, Trębicki P.   +5 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Evaluation of a new in-clinic test system to detect feline immunodeficiency virus and feline leukemia virus infection

, 2010
Background: Many in-house tests for the diagnosis of feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) infection are licensed for use in veterinary practice.
Strategic Infection Biology, Dep Infectieziekten Immunologie, Englert, T., Lutz, H., Sand, C., Egberink, H.F., Hartmann, K.   +6 more
core  

A "Bio-Assay" of Biology Tests

The American Biology Teacher, 1967
J. A. Easley,, Elizabeth Kendzior, Robert Wallace   +2 more
openaire   +1 more source

Correction: Heat shock factor-1 alleviates ER-stress in Caenorhabditis elegans. [PDF]

Sci Rep
Ahmed S, Kovács D, Kovács M, Kosztelnik M, Hotzi B, Sigmond T, Saskői É, Vincze VV, Erdélyi V, Deák V, Stiller I, Vellai T, Barna J.   +12 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The Tuberculin Test and its Role in the Strategic Management and Eradication of Tuberculosis in Cattle

, 2011
This thesis explores the necessity for bovine tuberculosis (bTB) eradication; considers the use the tuberculin test as a tool in bTB eradication and explores the need to select the optimal test methodology, to evaluate outcomes of existing procedures and
Strategic Infection Biology, Dep Infectieziekten Immunologie, Good, M.   +2 more
core  

Correction: Heparanase (HPSE) genetic variants as prognostic indicators in ovarian cancer: evidence from discovery and validation cohorts. [PDF]

Mol Biol Rep
de Melo IG, Tavares V, Savva-Bordalo J, Rei M, Liz-Pimenta J, Pereira D, Medeiros R.   +6 more
europepmc   +1 more source