Results 151 to 160 of about 1,766,427 (312)
Development and validation of a thinking skills test for high school students in biology
, 1999 This study develops and validates a test which measured the thinking skills of second year high school students in biology. It also seeks to identify the characteristics of the developed test in terms of its validity and reliability and, the norms of the
Lim, Florentina C.
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Nonparametric statistical test approaches in genetics data
, 2016 The biggest challenge of genetic research lies in significant and intellectual analysis of the large and complex data sets generated by the cutting edge techniques like massively parallel DNA sequencing and genome wide analysis.
Saroj, RAKESH Kumar; Department of Kayachikitsa Institute of Medical Sciences,Banaras Hindu University +2 more
core
Asian Journal of Assessment in Teaching and Learning, 2016 This study empirically analyzed the item difficulty and discrimination indices of senior school certificate examination SSCE multiple choice biology tests used by West African Examinations Council and National Examinations Council in Nigeria.
OLUTOLA -, Adekunle Thomas
doaj
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
A multiscale, Bayesian inference approach to augment mechanistic models of cell signaling with machine-learning predictions of binding affinity. [PDF]
PLoS Comput BiolHuber HA, Finley SD.
europepmc +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
A CURE for synthetic regulation of gene expression: rapid screening of guide RNA efficacy as a framework for enabling undergraduate research in plant synthetic biology. [PDF]
Synth Biol (Oxf)Bull T +22 more
europepmc +1 more source