Results 161 to 170 of about 1,730,969 (264)

Implementation strategies to increase Malawian health care workers' knowledge about and self-efficacy to recommend HPV vaccination: A pilot study. [PDF]

PLOS Glob Public Health
Moucheraud C, Phiri S, Phiri K, Kalande P, Makwaya A, Kamtsendero L, Chimbaka H, Gürpınar NG, Hagstrom C, van Oosterhout JJ, Szilagyi PG, Guastaferro K, Hoffman RM.   +12 more
europepmc   +1 more source

Academic Test HSC Biology Practice Test PDF

This PDF document provides a comprehensive practice test designed for students preparing for the Higher School Certificate (HSC) in Biology. It includes a range of question types, including multiple-choice, short answer, and extended response questions, reflecting the format and content areas of the actual HSC examination.
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Erratum: Comparative genomics reveals high prophage diversity and horizontal gene transfer of effectors and phage defence systems in the <i>Pseudomonas syringae</i> complex. [PDF]

Microb Genom
Holtappels D, Rickus GEJ, Morgan T, de Rezende RR, Koskella B, Alfenas-Zerbini P.   +5 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Cows visually discriminate and cross-modally recognise familiar and unfamiliar human faces in videos. [PDF]

PLoS One
Amichaud O, Lemarchand J, Cornilleau F, Jardat P, Ferreira VHB, Calandreau L, Lansade L.   +6 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

A statistical framework for comparing epidemic forests. [PDF]

PLoS Comput Biol
Geismar C, White PJ, Cori A, Jombart T.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Fingolimod increases cellular resistance to HIV-1 infection and limits viral reservoir size in peripheral CD4+ T-cells. [PDF]

PLoS Pathog
Moraga E, Climent N, Sánchez-Molina A, Vicens-Artés S, Maleno MJ, Valero López G, Galera Peñaranda C, Ambrosioni J, Miró JM, Mallolas J, Albendín-Iglesias H, Alcamí J, Sánchez-Palomino S.   +12 more
europepmc   +1 more source