Results 251 to 260 of about 15,644,828 (310)

Differences in motivation for biology learning: A measurement invariance testing and latent mean comparison approach

Ting Dai, Kuan Xing, Avi Kaplan, Jennifer G. Cromley, Kyle Mara, Tony Perez   +5 more
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Microbial diversity in drug-naïve Parkinson's disease patients. [PDF]

PLoS One
Papić E, Rački V, Hero M, Zimani AN, Čižek Sajko M, Rožmarić G, Starčević Čizmarević N, Ostojić S, Kapović M, Hauser G, Maver A, Peterlin B, Kovanda A, Vuletić V.   +13 more
europepmc   +1 more source

Diffusion Smart-seq3 of breast cancer spheroids to explore spatial tumor biology and test evolutionary principles of tumor heterogeneity

Antony Cougnoux, Loay Mahmoud, Per Johnsson, Alper Eroğlu, Louise Gsell, Jakob Rosenbauer, Rickard Sandberg, Jean Hausser   +7 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

How thoughtful experimental design can empower biologists in the omics era. [PDF]

Nat Commun
Wagner MR, Kleiner M.
europepmc   +1 more source

Assessing customer satisfaction: the case of test prescribers at the clinical biology laboratory of Centre Muraz/ Institut National de Santé Publique, Burkina Faso

Dame Yenyetou, Issouf Sanou, Chérileila Thiombiano, Bakary Diamoutany Sogodogo, A Sanou, Soufiane Sanou, Mamoudou Cissé, Amariane Koné, Aline R. Ouoba, Dramane Kania, Michel Kiréopori Gomgnimbou, Ibrahim Sangaré, Abdoul–Salam Ouédraogo   +12 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Biotechnological Preparedness for Novel Pandemics: Diagnostic Performance of IVDS Against SARS-CoV-2. [PDF]

Microbiologyopen
Kavruk M, Ercan M, Borsa BA, Özalp VC, Hernandez FJ.   +4 more
europepmc   +1 more source

Practicality test of SaLDI biology learning model integrated with TPACK on biology materials

Suhardi Aldi, Adnan Adnan, Andi Asmawati Azis   +2 more
openalex   +1 more source