Results 31 to 40 of about 271,303 (291)

AVALIAÇÃO DA ATIVIDADE MUTAGÊNICA DA TALIDOMIDA PELO TESTE DE AMES

Revista Eletrônica de Farmácia, 2007
A reintroducao da talidomida, reconhecidamente teratogenica, como farmaco potencial em uma serie de doencas como por exemplo SIDA, câncer, tuberculose, artrite reumatoide, doenca de Crohn, mieloma e sindromes mielodisplasicas requer a avaliacao do potencial genotoxico para uso em humanos.
openaire   +2 more sources

Mutagenicity assessment of aerosols in emissions from wood combustion [PDF]

, 2011
Mestrado em Estudos AmbientaisPolycyclic aromatic hydrocarbon (PAH) extracts of PM2.5 collected from combustion of seven wood species and briquettes were tested for mutagenic activities using Ames test with Salmonella typhimurium TA98 and TA100.
Binh Ngan Vu
core   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

What Are S0 Galaxies?

, 2009
The data collected in the Shapley-Ames catalog of bright galaxies show that lenticular (S0) galaxies are typically about a magnitude fainter than both elliptical (E) and early spiral (Sa) galaxies.
Hubble, Komatsu ., Sandage, Sandage, Sandage, Sidney van den Bergh   +5 more
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Comparative Epidemiological Studies on Gallbladder Cancer between Chile and Japan

Estudios Atacameños, 1998
Se ha realizado un estudio del cáncer vesicular entre 1991 y 1998 en Chile. Presentamos los principales hallazgos encontrados en esta investigación y se comparan con los datos equivalentes de Japón. 1) Hemos examinado el índice de mortalidad del cáncer
Masaharu Yamamoto, Iván Serra, A. Calvo, H. Watanabe, K. Endoh, N. Shibuya, K. Nakamura   +6 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Genotoxic evaluation of sludge from Matanza-Riachuelo basin under the influence of different uses of land [PDF]

, 2016
El Río Matanza-Riachuelo y sus afluentes atraviesan zonas con diferente grado de contaminación generada por lasactividades agrícola-ganaderas, urbana e industrial.
Biruk, Lucia Nadia, Etcheverry, Jimena, Fabrizio de Iorio, Alicia Rosa, Filippetto, Javier, Magdaleno, Anahí, Moretton, Juan Agustin, Weigant, Cristian   +6 more
core  

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Leitfaden zum User-Testing des VR-Spiels "Navigation der Südsee" am 19.09.2019

, 2021
Dieses Arbeitspapier ist Teil der Online-Publikation von Dietmar Fuhrmann, Cristina Navarro und Josefine Otte "Mit der Zielgruppe testen! Wie Kinder im Museum mitgestalten. Eine Studie im Teilprojekt Visitor Journeys neu gedacht im Verbundprojekt museum4punkt0", entstanden im Verbundprojekt museum4punkt0 – Digitale Strategien für das Museum der Zukunft,
openaire   +1 more source