Results 241 to 250 of about 601,408 (316)

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter Lange, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

Conductive Hydrogels for Exogenous Sensing and Cell Fate Control

Advanced Materials, EarlyView.
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar, Carlos Alejandro Jimenez‐Rodriguez, Railia Biktimirova, Ilka Hermes, Thomas Kurth, My Duyen Pham, Mikhail Tsurkan, Jens Friedrichs, Francis L. C. Morgan, Hans Kleemann, Olga Guskova, Uwe Freudenberg, Peter Fratzl, Carsten Werner, Christoph Tondera, Ivan R. Minev   +15 more
wiley   +1 more source

Montelukast suppresses NLRP3 inflammasome activation as a potential prophylactic agent against gout arthritis flares. [PDF]

J Inflamm (Lond)
Shippy DC, Evered AH, Ulland TK.
europepmc   +1 more source

Study of a Novel Bi‐Layered Thermoplastic Polyurethane Patch for Congenital Diaphragmatic Hernia

Advanced Materials Interfaces, EarlyView.
Large congenital diaphragmatic hernia remains a challenge due to the poor compatibility of current prostheses. To tackle this problem, a bilayer thermoplastic polyurethane patch with tunable mechanical properties is engineered, whose fibrous side supports rapid fibroblast and myoblast colonization, while the smooth film limits adhesions.
Guillaume Leks, Julie Favre, Manon Zislin, Rodolphe Migneret, Jordana Hirtzel, Vincent Ball, Cendrine Seguin, Anne Hebraud, Emeline Lobry, Guy Schlatter, Nadia Bahlouli, Hamdi Jmal, Benoît Frisch, Sylvie Fournel, Isabelle Talon   +14 more
wiley   +1 more source

Urinary carbonic anhydrase 1 excretion is a marker of hemolysis-triggering conditions suitable for point-of-care testing.

Blood Glob Hematol
Hulikova A, Wang Z, Broomfield H, Robinson J, Healy M, Figueroa-Mujíca RJ, Gamboa D, Torres K, Ammanath G, Hartono D, Siow RC, Engledow S, Srinamon K, Ghose A, Plewes K, Dondorp AM, Roy NBA, Villafuerte FC, Khan H, Swietach P.   +19 more
europepmc   +1 more source

Rapid and visual dual-color lateral flow immunoassay for african swine fever virus antibody detection. [PDF]

Appl Microbiol Biotechnol
Chen J, Shi Z, Ru Y, Li S, Zhu Y, Luo J, Jia C, Zhang X, Wei J, Zhou J, Liao H, Zhang L, Tian H, Zheng H.   +13 more
europepmc   +1 more source

Comparative Evaluation of IgM Enzyme-Linked Immunosorbent Assay (ELISA) and Real-Time PCR for the Early Diagnosis of Scrub Typhus in Patients With Febrile Illness. [PDF]

Cureus
Sherawat P, Khayyam N, Sharma SP, Singh J, Dalela G.   +4 more
europepmc   +1 more source

Detection of anti-dsDNA by IgG ELISA test using two different sources of antigens: calf thymus versus E.coli

, 2009
M Mohammadi, A Mirjalili, Habibi Gh, Falahi Sh, A Sarafnejad, A Eatemadi, Boutorabi SM   +6 more
openalex   +1 more source

Human brucellosis in pregnancy in western Uganda: High seroprevalence and health risk factors identified in a cross-sectional study. [PDF]

PLoS Negl Trop Dis
Virginia W, Ishimwe MPS, Kazigo AK, Tshilumba T, Rukamba JD, Pius T, Isse SAS, Hakizimana T.   +7 more
europepmc   +1 more source

Seroprevalence and Associated Factors of Camel and Human Brucellosis in Dire District, Southern Ethiopia: A One-Health Perspective. [PDF]

Vet Med Sci
Ambaw YG, Kosi DG, Mengistu S, Kallu SA.
europepmc   +1 more source