Results 41 to 50 of about 985,876 (361)

Development of a species-specific coproantigen ELISA for human taenia solium taeniasis [PDF]

open access: yes, 2009
Taenia solium causes human neurocysticercosis and is endemic in underdeveloped countries where backyard pig keeping is common. Microscopic fecal diagnostic methods for human T.
Allan, JC   +7 more
core  

Untersuchung zur Serodiagnostik von Cox B – Viren - Ein Methodenvergleich [PDF]

open access: yes, 2005
Enterovirus- bzw. CBV-Infektionen können eine Vielzahl klinischer Symptome hervor-rufen, wobei in der Regel allenfalls eine Verdachtsdiagnose gestellt werden kann.
Sina, Alireza   +1 more
core   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard   +8 more
wiley   +1 more source

Development of a Sandwich ELISA to Measure Exposure to Occupational Cow Hair Allergens [PDF]

open access: yes, 2011
Background: Cow hair and dander are important inducers of occupational allergies in cattle-exposed farmers. To estimate allergen exposure in farming environments, a sensitive enzyme immunoassay was developed to measure cow hair allergens.
Angelika Flagge   +36 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Development of a LAMP assay for detection of Leishmania infantum infection in dogs using conjunctival swab samples [PDF]

open access: yes, 2015
Background: Leishmania infantum infections in dogs play a crucial role in the transmission of pathogens causing visceral leishmaniasis to humans in the Gansu province, northwest China. To be able to control zoonotic transmission of the parasite to humans,
A Moshfe   +48 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Quantification of lysozyme in hyperimune egg white aquous extracts and in biological products by SANDWICH ELISA test [PDF]

open access: yesMedicamentul Veterinar, 2020
Lysozyme is a biologically active protein present in egg whites, having an essential role in the immune defense of the embryo. Due to its antimicrobial properties, it is extracted and used in the composition of various products as a preservative and/or a
Viorica Chiurciu   +4 more
doaj  

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