Results 41 to 50 of about 615,347 (268)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
PLoS ONE, 2015 BackgroundLeptospirosis is diagnosed on clinical grounds, and confirmed by microscopic agglutination test (MAT). IgM-ELISA (Serion-Virion) and immunochromatography test (Leptocheck-WB) are two immunodiagnostic assays for leptospirosis. Their sensitivity,
Roshan Niloofa +11 more
doaj +1 more source
EVALUATION OF TWO RAPID DIAGNOSTIC METHODS FOR ROTAVIRUS IN BOVINE FAECES [PDF]
Kafrelsheikh Veterinary Medical Journal, 2012 Rotaviral infections are common cause of economically important calf diarrhea through out the world, Specific, rapid and accurate diagnosis are required to control the disease and animal loss, dipstick (imunnochromatographical test) and enzyme linked ...
Hanaa, A. A. Ghoniem, Hala, A. Salem
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
ELISA Cut-off Point for the Diagnosis of Human Brucellosis; a Comparison with Serum Agglutination Test [PDF]
Iranian Journal of Medical Sciences, 2012 Background: Brucellosis is a world-wide disease, which has a diverse clinical manifestation, and its diagnosis has to be proven by laboratory data. Serum agglutination test (SAT) is the most-widely used test for diagnosing brucellosis.
Anahita Sanaei Dashti +7 more
doaj
DETERMINATION OF CANINE DIROFILARIASIS BY ELISA METHOD AND MODIFIED KNOTT'S TEST
Archives of Veterinary Medicine, 2009 Canine dirofilariasis is a parasitic disease. The causative agent is Dirofilaria immitis or Dirofilaria repens. It may appear as skin or as a heart disease.
Sara Savić +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
NTU Journal of Pure SciencesCytomegalovirus is a member of herpes virus. As CMV affects many living cell, people are at risk of acquiring it especially pregnant women and can transmit it to their fetus. The purpose of this study is to compare two common methods for Cytomegalovirus
Zena Muayad Noraldeen +1 more
doaj +1 more source