Results 71 to 80 of about 986,956 (308)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Occurrence of the Leucine-to-Phenylalanine knockdown Resistance (kdr) Mutation in Anopheles Arabiensis Populations in Tanzania, Detected by a Simplified High-Throughput SSOP-ELISA Method. [PDF]

, 2006
Molecular markers of insecticide resistance can provide sensitive indicators of resistance development in malaria vector populations. Monitoring of insecticide resistance in vector populations is an important component of current malaria control ...
Alifrangis, Michael, Drakeley, Chris, Kulkarni, Manisha A, Kweka, Eliningaya, Lyimo, Issa, Magesa, Stephen, Malima, Robert, Matowo, Johnson, Mosha, Frank W, Peter, Justin, Rau, Manfred E, Rowland, Mark, Salanti, Ali   +12 more
core   +3 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Temporal trends in bulk milk antibodies to Salmonella, Neospora caninum, and Leptospira interrogans serovar hardjo in Irish dairy herds [PDF]

, 2012
peer-reviewedBulk milk samples were collected from 309 Irish dairy herds at four time points during 2009 and tested for antibodies to Salmonella spp., N. caninum, and L. hardjo, three abortifacient agents in Irish dairy herds. Of the 312 study herds, 49%
O'Doherty, Eugene, O'Grady, Luke, Sayers, Riona   +2 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Combined use of two rapid test in Legionella pneumophila infections

Microbiologia Medica, 2009
Legionella pneumophila serogroup 1 (LPSg1) is the prevalent cause of legionellosis in many geographical areas of the world. LPSg1 infection may presents a severe pulmonary disease whose clinical picture is undistinguishable from that of other ...
Gino Ciarrocchi, Marco D’anzeo, Maria Enrica Cimarelli, Brunilde Berti, Francesco Petrini   +4 more
doaj   +1 more source

Ecological Aspects and Conservation of Wild Grapevine Populations in the S.W. of the Iberian Peninsula [PDF]

, 2004
Populations of wild grapevine, Vitis vinifera L. subsp. sylvestris (Gmelin) Hegi, were discovered in S.W. of the Iberian Peninsula over the last years. Location, ecological aspects, sanitary characteristics, including the ELISA test to detect specific
Cantos Barragán, Manuel, Gallardo Cano, Antonio, Gómez Parrales, Isidoro Ángel, López Martínez, María Ángeles, Ocete Rubio, Rafael, Troncoso, Antonio   +5 more
core  

Cysticercosis and taeniasis cases diagnosed at two referral medical institutions, Belgium, 1990 to 2015 [PDF]

, 2019
Background: Few case reports on human infections with the beef tapeworm Taenia saginata and the pork tapeworm, Taenia solium, diagnosed in Belgium have been published, yet the grey literature suggests a higher number of cases.
Bottieau, Emmanuel, Dermauw, Veronique, Dorny, Pierre, Luyckx, Kim, Luyten, Leon, Van Bockstal, Lieselotte, Van Den Broucke, Steven   +6 more
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source