Results 141 to 150 of about 14,106,922 (303)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

CASQ. Coping Across Situations Questionnaire

open access: yes
Der CASQ erfasst das individuelle Bewältigungsverhalten von Jugendlichen in belastenden Situationen. 20 Bewältigungsstrategien in acht altersspezifischen Problembereichen werden den drei Subskalen "Aktive Bewältigung", "Internale Bewältigung" und ...
Seiffge-Krenke, I.
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Tractor Testing; Belt Power Test; Leroi Centaur

open access: yes, 1948
1948. Belt test no. 402. Centaur KV 48. with G. Olson, W. McPhail, Billy Bryan. Centaur KV-48 in the tractor test lab. A belt runs from the tractor pulley to the dynamometer in the adjacent room. Gordon Olson mans the dyno controls, W.
Nebraska Tractor Test Laboratory
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Tractor Testing; Belt Power Test; Caterpillar

open access: yes, 1940
Text states: "1940. Checking engine R.P.M. during test no. 357." The Caterpillar D-8 is shown from the rear, where the belt pulley is located. A test engineer is measuring the belt pulley RPM with a handheld Tachometer (an RPM counter) touching the ...
Nebraska Tractor Test Laboratory
core  

Peters et al. Delusions Inventory - German version

open access: yes
Die deutsche Adaptation des PDI, PDI-G, als Kurz- (k = 21 Items) und Langfassung (k = 40 Items) erfasst auf drei Dimensionen (Besorgnis, Zeitliche Beschäftigung, Überzeugungsstärke) subklinischen Wahn bei Erwachsenen.
Lincoln, T. M.
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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