Results 61 to 70 of about 23,270 (258)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Examining the impact of violations of local item independence assumption on test equating methods

International Journal of Assessment Tools in Education
This study investigates the impact of violating the local item independence assumption by loading certain items onto a second dimension on test equating errors in unidimensional and dichotomous tests.
Şeref Tan, Mehmet Fatih Doğuyurt
doaj   +1 more source

Testing for bias in weighted estimating equations [PDF]

Biostatistics, 2001
It is very common in regression analysis to encounter incompletely observed covariate information. A recent approach to analyse such data is weighted estimating equations (Robins, J. M., Rotnitzky, A. and Zhao, L. P. (1994), JASA, 89, 846-866, and Zhao, L. P., Lipsitz, S. R. and Lew, D. (1996), Biometrics, 52, 1165-1182).
Lipsitz, Stuart, Parzen, Michael, Molenberghs, Geert, Ibrahim, Joseph G.   +3 more
openaire   +4 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Penyetaraan (Equating) Ujian Akhir Sekolah Berstandar Nasional (UASBN) Dengan Teori Tes Klasik

Jurnal Pendidikan dan Kebudayaan, 2011
Since the enactment of the National Standard School Final Examination (UASBN) in school year 2007/2008, the province is authorized to construct exam questions based on the same lattice issued BSNP.
Arniati Prasedyawati Herkusumo
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Testing for Autocorrelation in Systems of Equations

, 2007
This paper deals with the problem of testing for the presence of autocorrelation in a system of general linear models (Seemingly Unrelated Regressions, SUR) when the model is formulated as a vector autoregression (VAR) with exogenous variables. The solution presented in this paper is a generalization of the h-statistic for the single equation single ...
openaire   +5 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

KARAKTERISTIK METODE PENYETARAAN SKOR TES UNTUK DATA DIKOTOMOS

Jurnal Penelitian dan Evaluasi Pendidikan, 2013
Penelitian ini bertujuan untuk menemukan: 1) akurasi estimasi parameter item pada test equating menggunakan metode Item Characteristic Curve (ICC). 2) sensitivitas metode linear yang terdiri atas Tucker - Levine score method dan Levine true score method ...
Nonoh Siti Aminah
doaj