Results 121 to 130 of about 7,596,315 (208)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Materials & DesignDigital control in manufacturing processes produces significant amounts of metadata. The production process metadata, such as thermal and optical measurements, enables a higher degree of property grading than uninstrumented manufacturing and feedback for
Mustafa Awd +4 more
doaj +1 more source
Verfahrensdokumentation für EVT: Essverhalten-Test
, 1999 Das Verfahren stellt ein quantitatives und qualitatives Maß für die Diagnose, die Stärke und die Erscheinungsform der Symptomatik von Bulimie zur Verfügung. Als Grundlage diente der Bulimia Test (BULIT) von Smith und Thelen (1984). Der EVT besteht aus 20
Böhm, B.
core +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Adaptação do inventário de Estratégias de Coping¹ de Folkman e Lazarus para o português
Psicologia USPEste estudo tem por objetivo adaptar o Inventário de Estratégias de Coping para o português. Para a tradução foram utilizados quatro juízes, que indicaram ser a tradução fidedigna ao inventário original com relação à interpretação das questões.
Mariangela Gentil Savóia +2 more
doaj
Screening to Assess Psychosocial Follow-Up Needs in Pediatric Oncology (Self- and Parent-Report)
Der NPO-11 dient als Screening zur Einschätzung des psychosozialen Nachsorgebedarfs in der pädiatrischen Onkologie im Selbst- und Elternbericht. Anhand von Expertenangaben wurden jeweils 11 Items für die Nachsorgebereiche Progredienzangst, Traurigkeit ...
Kamm-Thonwart, R. +8 more
core +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
CASQ. Coping Across Situations Questionnaire
Der CASQ erfasst das individuelle Bewältigungsverhalten von Jugendlichen in belastenden Situationen. 20 Bewältigungsstrategien in acht altersspezifischen Problembereichen werden den drei Subskalen "Aktive Bewältigung", "Internale Bewältigung" und ...
Seiffge-Krenke, I.
core +1 more source