Results 121 to 130 of about 1,035,244 (264)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Depth Sensor-Based Instrumentation of the Fukuda Stepping Test: Reliability and Clinical Associations in Older Adults. [PDF]

Sensors (Basel)
Ünal HT, Koçak M, Çetin SY, Kara ÖK, Doğan M.   +4 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

A Standardised Car Seat Transfer Test: Reliability and Concurrent Validity. [PDF]

Occup Ther Int
de Campos TF, Wolden M, March MK, Hewawasam D, Boumelhem B, Spurr JJ, Khoury JM, Vertzyas N, Faux SG, Gass GC, Mungovan SF.   +10 more
europepmc   +1 more source

Re-test reliability and internal consistency of EEG alpha-band oscillations in older adults with chronic knee pain. [PDF]

Clin Neurophysiol, 2020
Rocha HA, Marks J, Woods AJ, Staud R, Sibille K, Keil A.   +5 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Development, Validity, and Test Reliability and Reproducibility of Facial Palsy-Associated Facial Movement: A Cross-Sectional Study. [PDF]

J Pharm Bioallied Sci
Deshpande D, Yaramati KC, Bobba CT, Priya M, Pasupuleti SC, Gubbala SA, Thakkar N.   +6 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Intra- and Inter-Rater Reliability, Parallel Test Reliability, and Internal Consistency of the Tuning Fork and Monofilament Tests. [PDF]

Bioengineering (Basel)
Veldema J, Sasse L, Straub J, Klemm M, Grönheim LV, Steingräber T.   +5 more
europepmc   +1 more source