Results 51 to 60 of about 7,596,315 (208)
The current article gives an overview of the development and problems related to the advancement of the national examination in English in Estonia over a ten-year period, starting from its launch in 1997.
Suliko Liiv, Ene Alas
doaj +1 more source
Verfahrensdokumentation für NaWi-Test: Test über das Wissen im nachhaltigen Wirtschaften
Der NaWi-Test ist ein standardisierter Test zur Erfassung des Fachwissens über nachhaltiges Wirtschaften von Auszubildenden, Schülerinnen und Schülern, Lehrkräften sowie Beschäftigten in Unternehmen. Er umfasst 15 empirisch geprüfte Aufgaben, die jeweils
Heubischl, S. +5 more
core +1 more source
Reliability approach for safe designing on a locking system [PDF]
The aim of this work is to predict the failure probability of a locking system. This failure probability is assessed using complementary methods: the First-Order Reliability Method (FORM) and Second-Order Reliability Method (SORM) as approximated methods,
ARNOUX, Philippe +3 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
First demonstration of in-memory computing crossbar using multi-level Cell FeFET
Advancements in AI led to the emergence of in-memory-computing architectures as a promising solution for the associated computing and memory challenges.
Taha Soliman +8 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Tool to assess the groundstroke technique of preadolescent tennis players
ObjectiveIn this study, we develop a tool that can be used by tennis coaches to evaluate the groundstroke (forehand and backhand) technique of preadolescent tennis players.MethodsThe participants of the study were 60 children (30 males and 30 females ...
Hakan Diler +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

