Results 71 to 80 of about 1,035,244 (264)
AtmosphereIndoor air pollution is a major cause of noncommunicable diseases, and increasing people’s knowledge about the related risks is a key action for prevention.
Letizia Appolloni +2 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
DronesMaritime dynamic observation missions, such as environmental monitoring, marine ranching inspection, and emergency response, typically require large-scale and high-efficiency operations in complex and variable maritime environments.
Dongying Feng +5 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
On the Unreliability of Test-Retest Reliability
Applied Psychological MeasurementThe Test-Retest Coefficient (TRC) is a central metric of reliability in Classical Test Theory and modern psychological assessments. Originally developed by early 20th-century psychometri-cians, it relies on the assumptions of fixed (i.e., perfectly stable) true scores and independent error scores. However, these assumptions are rarely, if ever, tested,
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Yantu gongcheng xuebaoA series of centrifugal model tests are conducted by selecting the linear error, average amplitude error and response rate as the indice. Based on the tunnel model, a new flexibly soft contact earth pressure cell ESP-Ⅱ and two internationally ...
LIU Yuanpeng 1, 2, TANG Zhaoguang 1, 2, LI Yurun 3, WANG Yongzhi 1, 2, ZHU Yaoting4, LIU Hongshuai5
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source