Results 131 to 140 of about 263,174 (307)

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

IMPROVING SUPPORT VECTOR MACHINE PERFORMANCE WITH BINARY GAUSSIAN IMPROVED WHALE OPTIMIZATION ALGORITHM: A CASE STUDY ON DIABETES DATA

Barekeng
Diabetes mellitus is a chronic condition with high blood sugar that can cause severe organ damage, affecting all ages globally. Early diagnosis is crucial for improving patients' quality of life, and machine learning offers a promising approach.
Haidar Ahmad Fajri, Safrizal Ardana Ardiyansa, Syaiful Anam, Natasha Clarrisa Maharani, Eric Julianto   +4 more
doaj   +1 more source

Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS

Advanced Science, EarlyView.
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi, Di Tang, Johan Malmström, Yasaman Karami, Hamed Khakzad   +4 more
wiley   +1 more source

Identification of Risk Factors in Patients with Recurrent Cystitis May Improve Individualized Management

Diagnostics
Background/Objectives: Management of acute episodes of lower urinary tract infection (LUTI) depends on whether they are sporadic or recurrent. We aimed to define factors that differentiate patients with acute sporadic cystitis (AC) from those with ...
Jakhongir F. Alidjanov, Ulugbek A. Khudaybergenov, Khurshid B. Khudayberdiev, Jennifer Kranz, Laila Schneidewind, Fabian P. Stangl, José Medina-Polo, Adrian Pilatz, Tommaso Cai, Kurt G. Naber, Florian M. Wagenlehner, Truls E. Bjerklund Johansen   +11 more
doaj   +1 more source

Memory for prices and the euro cash changeover: An analysis for cinema prices in Italy [PDF]

The question addressed by this study is whether consumers remember past prices correctly. We test Italian citizensÂ’ memory for cinema prices with questionnaires distributed to moviegoers.
Clelia Rossi-Arnaud, Paolo Del Giovane, Vincenzo Cestari   +2 more
core  

Integrative Analyses Identify a cGAS‐STING Pathway‐Driven Signature With Context‐Dependent Roles in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Zhang et al. identify M7core, a critical cGAS‐STING pathway‐driven gene signature that is activated in most lupus patients’ blood and links to lupus disease severity, lymphopenia, and lupus nephritis. They further reveal the diagnostic and pathogenic characteristics of M7core and emphasize the importance of assessing pathway activity before initiating ...
Lele Zhang, Ming‐Ju Amy Lyu, Ze Hong, Jing Sun, Lan Guo, Jiameng Hu, Munire Maimaiti, Chenhui Li, Jinyi Song, Xiang Zhang, Huansha Yu, Chen Wang, Xuan Wang, Haiyang Hu   +13 more
wiley   +1 more source

Central Bank Transparency: A Market Indicator [PDF]

It is widely believed that monetary policy outcomes are generally enhanced if the conduct of policy by the central bank is widely understood by other agents in the economy.
Iris Biefang-Frisancho Mariscal, Peter Howells   +1 more
core  

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Vacuum–Laser Fabrication of Programmable Soft Actuators

Advanced Science, EarlyView.
A rapid and accessible fabrication strategy for inflatable soft actuators is presented, combining vacuum sealing with laser cutting of low‐cost thermoplastic pouches. The method enables precise sealing, fast fabrication, and programmable multi‐cell geometries.
Ashkan Rezanejad, Mostafa Mousa, Yuxuan Wang, Michael Adlerstein, Junke Yao, Antonio E. Forte   +5 more
wiley   +1 more source

Rural-urban disparity in uptaking skilled antenatal care visits by pregnant women in Bangladesh: Zero and One Inflated Poisson regression model.

PLoS ONE
BackgroundUtilization of maternal health care services, specifically, antenatal care services from skilled health providers have been given utmost priority in low- and middle-income countries over years with a view of mitigating complications during ...
Lubana Tanvia, M Ershadul Haque, Wasimul Bari   +2 more
doaj   +1 more source