Results 131 to 140 of about 814,853 (265)

Hyperhidrosis quality of life index (HidroQoL): further validation by applying classical test theory and item response theory using data from a phase III clinical trial. [PDF]

J Patient Rep Outcomes, 2023
Donhauser T, Apfelbacher C, Kann G, Masur C, Kamudoni P, Salek S, Abels C, Gabes M.   +7 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Using Classical Test Theory to Determine the Psychometric Properties of the Italian Version of the Feeding/Swallowing Impact Survey. [PDF]

J Clin Med
Crispiatico V, Baffi A, Buratti MA, Montali L, Speyer R.   +4 more
europepmc   +1 more source

Validation of the Connor-Davidson Resilience Scale-10 in South Africa: Item Response Theory and Classical Test Theory. [PDF]

Psychol Res Behav Manag, 2022
Pretorius TB, Padmanabhanunni A.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

A Longitudinal Study on Psychometric Properties of the Simplified Chinese Version of FACT-Hep for Patients with Hepatocellular Carcinoma by Classical Test Theory and Generalizability Theory. [PDF]

Cancer Manag Res
Wang Y, Ding S, Meng Q, Cun Y, Li G, Chen Y, Wan C.   +6 more
europepmc   +1 more source

Identifying meaningful change on PROMIS short forms in cancer patients: a comparison of item response theory and classic test theory frameworks. [PDF]

Qual Life Res, 2023
Lee MK, Peipert JD, Cella D, Yost KJ, Eton DT, Novotny PJ, Sloan JA, Dueck AC.   +7 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Development and validation of the general module of the quality of life instruments for chronic diseases QLICD-GM(V2.0) : a large sample study based on classical test theory and item response theory. [PDF]

Health Qual Life Outcomes
Wan C, Zhang X, Qiao L, Li W, Chen Y, Ma W, Xue H, Quan P, Wang D.   +8 more
europepmc   +1 more source

Development of the Paranormal and Supernatural Beliefs Scale using classical and modern test theory. [PDF]

BMC Psychol, 2021
Dean CE, Akhtar S, Gale TM, Irvine K, Wiseman R, Laws KR.   +5 more
europepmc   +1 more source