Results 161 to 170 of about 5,224,671 (298)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

A Longitudinal Study on Psychometric Properties of the Simplified Chinese Version of FACT-Hep for Patients with Hepatocellular Carcinoma by Classical Test Theory and Generalizability Theory. [PDF]

Cancer Manag Res
Wang Y, Ding S, Meng Q, Cun Y, Li G, Chen Y, Wan C.   +6 more
europepmc   +1 more source

Development of the Paranormal and Supernatural Beliefs Scale using classical and modern test theory. [PDF]

BMC Psychol, 2021
Dean CE, Akhtar S, Gale TM, Irvine K, Wiseman R, Laws KR.   +5 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Development and validation of the general module of the quality of life instruments for chronic diseases QLICD-GM(V2.0) : a large sample study based on classical test theory and item response theory. [PDF]

Health Qual Life Outcomes
Wan C, Zhang X, Qiao L, Li W, Chen Y, Ma W, Xue H, Quan P, Wang D.   +8 more
europepmc   +1 more source

Validating Insomnia Severity Index (ISI) in a Bangladeshi Population: Using Classical Test Theory and Rasch Analysis. [PDF]

Int J Environ Res Public Health, 2021
Mamun MA, Alimoradi Z, Gozal D, Manzar MD, Broström A, Lin CY, Huang RY, Pakpour AH.   +7 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Evaluating the Insomnia Severity Index among South African first responders: evidence from classical test theory, Rasch, and Mokken analyses. [PDF]

Front Sleep
Pretorius TB, Padmanabhanunni A.
europepmc   +1 more source

Using path analysis to test theory of change: a quantitative process evaluation of the MapSan trial. [PDF]

BMC Public Health, 2021
Bick S, Buxton H, Chase RP, Ross I, Adriano Z, Capone D, Knee J, Brown J, Nalá R, Cumming O, Dreibelbis R.   +10 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source