Results 191 to 200 of about 5,224,671 (298)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Further validation of the Chinese short Warwick Edinburgh mental wellbeing scale in the adult population of Macau: an application of classic test theory and item response theory. [PDF]

Front Psychiatry
Lam LT, Lam MK.
europepmc   +1 more source

Reliability, Validity, and Unidimensionality of the Korean Version of the Pornography Craving Questionnaire Based on the Classical Test Theory and Item Response Theory. [PDF]

Psychiatry Investig, 2021
Kim SR, Bhang SY, Lim EY, Huh S, Lee SK, Kraus SW, Potenza MN.   +6 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Health behavior inventory - short form: a Chinese validation study using classical test theory and item response theory. [PDF]

BMC Public Health
Tong LK, Au ML, Zheng MR, Liu YB, Fu GL, Li YY.   +5 more
europepmc   +1 more source

Reliability and validity of the Pittsburgh Sleep Quality Index among frontline COVID-19 health care workers using classical test theory and item response theory. [PDF]

J Clin Sleep Med, 2022
Wang L, Wu YX, Lin YQ, Wang L, Zeng ZN, Xie XL, Chen QY, Wei SC.   +7 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Correction: Psychometric evaluation of the study interest questionnaire-short form among Chinese nursing students based on classical test theory and item response theory. [PDF]

BMC Nurs
Li YY, Tong LK, Au ML, Ng WI, Wang SC, Liu Y, Zhong L, Shen Y, Qiu X.   +8 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Comparing the psychometric evidence of the Depression, Anxiety, and Stress Scale-21 (DASS-21) between Spanish and Chinese primary schoolteachers: insights from classical test theory and rasch analysis. [PDF]

BMC Psychol
Wang X, Cao CH, Liao XL, Jiang XY, Griffiths MD, Chen IH, Lin CY, Malas O.   +7 more
europepmc   +1 more source