Results 201 to 210 of about 5,188,056 (277)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

The translation and validation of the surgical anxiety questionnaire into the modern standard Arabic language: results from classical test theory and item response theory analyses. [PDF]

BMC Psychiatry
Alghamdi AA, Alghuthayr K, Alqahtani SSSMM, Alshahrani ZA, Asiri AM, Ghazzawi H, Helmy M, Trabelsi K, Husni M, Jahrami H.   +9 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Translating and validating the Ghosting Questionnaire into Arabic: results from classical test theory and item response theory analyses : Short title: the arabic version of the Ghosting Questionnaire. [PDF]

BMC Psychol
Husain W, Salem AAMS, Ammar A, Trabelsi K, Ghazzawi H, Saif Z, Helmy M, Pandi-Perumal SR, Seeman MV, Pakpour AH, Jahrami H.   +10 more
europepmc   +1 more source

Experimental Manipulations to Test Theory-Driven Mechanisms of Cognitive Behavior Therapy. [PDF]

Front Psychiatry, 2020
Southward MW, Sauer-Zavala S.
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Test your theory [PDF]

Nature Physics, 2020
openaire   +1 more source

Item analysis on the quality of life scale for anxiety disorders QLICD-AD(V2.0) based on classical test theory and item response theory. [PDF]

Ann Gen Psychiatry
Shi H, Ren Y, Xian J, Ding H, Liu Y, Wan C.   +5 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Validation of the eHealth Literacy Scale Instrument in a Restless Legs Syndrome Population: Classical Test Theory and Rasch Analysis Study.

J Med Internet Res
Georgsson M, Odzakovic E, Björk M, Kaldo V, Jernelöv S, Blom K, Ulander M, Fridlund B, Knutsson S, Sandlund C, Pakpour A, Broström A.   +11 more
europepmc   +1 more source