Results 61 to 70 of about 5,188,056 (277)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Applying SMT Solvers to the Test Template Framework
The Test Template Framework (TTF) is a model-based testing method for the Z notation. In the TTF, test cases are generated from test specifications, which are predicates written in Z.
Alexander K. Petrenko +32 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Quarkonium polarization as a test of non-relativistic effective theory [PDF]
I compare current approaches to quarkonium production with regard to what they tell us about quarkonium polarization. Predictions for $J/\psi$ polarization in hadron-hadron and photon-hadron collisions are summarized.Comment: 6 pages, LaTeX, 3 figures ...
Beneke, M.
core +1 more source
The de Finetti theorem for test spaces [PDF]
We prove a de Finetti theorem for exchangeable sequences of states on test spaces, where a test space is a generalization of the sample space of classical probability theory and the Hilbert space of quantum theory.
Barrett, Jonathan, Leifer, Matthew
core +3 more sources
Aim and Background: The need for belonging has multiple and lasting effects on emotional patterns, cognitive processing, and optimal psychological functioning, and its low levels are associated with mental and physical illness.
Farhad Tanhaye Reshvanloo +2 more
doaj
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A perturbation density functional theory for the competition between inter and intramolecular association [PDF]
Using the framework of Wertheim's thermodynamic perturbation theory we develop the first density functional theory which accounts for intramolecular association in chain molecules.
Alejandro J. García-Cuéllar +3 more
core +2 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source

