Results 21 to 30 of about 955,170 (266)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
DiWi - Test zum Wissen über verschiedene Diversitätsbereiche von (angehenden) Lehrkräften
, 2022 Der Test (DiWi) erfasst das deklarative Faktenwissen über verschiedene Diversitätsbereiche von (angehenden) Lehrkräften. Er liegt in einer Langform (DiWi: 142 Items) und einer Kurzform (DiWi-K: 36 Items) mit den fünf Subskalen Förderschwerpunkt ...
Steinmayr, R., Tometten, L., Heyder, A.
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Verfahrensdokumentation für EVT: Essverhalten-Test
, 1999 Das Verfahren stellt ein quantitatives und qualitatives Maß für die Diagnose, die Stärke und die Erscheinungsform der Symptomatik von Bulimie zur Verfügung. Als Grundlage diente der Bulimia Test (BULIT) von Smith und Thelen (1984). Der EVT besteht aus 20
Böhm, B.
core +1 more source
Predictive validity of the UK clinical aptitude test in the final years of medical school:a prospective cohort study [PDF]
, 2014 Background: The UK Clinical Aptitude Test (UKCAT) was designed to address issues identified with traditional methods of selection. This study aims to examine the predictive validity of the UKCAT and compare this to traditional selection methods in the ...
Alistair Mathieson +9 more
core +1 more source
Die SDS dient der Erfassung des Schweregrades einer depressiven Stimmung anhand von vier Subskalen (motivationale, emotionale, kognitive und somatische Anteile einer depressiven Symptomatik).
Satow, L.
core +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
PCS-Q-G. Parental Caregiving Style Questionnaire – German Version
Der PCS-Q-G dient der retrospektiven Erfassung des elterlichen Fürsorgeverhaltens. In Analogie zum 3-Kategorien-Modell von Bindung unterscheidet das Instrument zwischen den drei Stilen „warm/aufmerksam“, „ambivalent/inkonsistent“ und „kalt/abweisend ...
Rohmann, E., Neumann, E.
core +1 more source