Results 181 to 190 of about 114,872 (265)

ASB9 promotes ubiquitin-mediated degradation of TNP2 to facilitate histone-to-protamine transition in humans and mice. [PDF]

Proc Natl Acad Sci U S A
Zhao S, Shen G, Ruan T, Zhuo L, Wang Y, Wang X, Tian Y, Tang X, Ma J, Jiang X, Zhang Y, Jiang C, Xie A, Shang X, Wang J, Yang Y, Shen Y.   +16 more
europepmc   +1 more source

Multiomics Insights Into AL Amyloidosis

Medicine Bulletin, EarlyView.
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang, Ziru Huang, Haoxiang Tang, Xianrun Pan, Rong Wang, Dingding Zhang, Jian Huang   +6 more
wiley   +1 more source

Germline and male somatic determinants of sperm length divergence in Drosophila: implications for postcopulatory sexual selection. [PDF]

Genetics
Nishimura K, Asaoka M, Takano-Shimizu-Kouno T.   +2 more
europepmc   +1 more source

scRNA-seq reveals different cell clusters in the testes of Mongolian cattle and EGR1/FOS/JUN regulation in Sertoli cells. [PDF]

Sci Rep
Gao S, Zhang S, Ren H, Yang H, Wang L, He J, Zhang J, Zhang G, Mengke B, Zhu L, Qi Q, Aierqing S, Fan R, Herrid M.   +13 more
europepmc   +1 more source

Morphological and molecular identification of amphistomes occurring in cattle in Zimbabwe. [PDF]

Parasitol Res
Nyagura I, Malatji MP, Sibula MS, Ngcamphalala PI, Mukaratirwa S.   +4 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Loss of ABC transporters, White, Brown, and Scarlet, prevents increase in mitotic divisions of germline stem cells in response to mating in Drosophila melanogaster. [PDF]

PLoS One
Wright MP, Vladimirova A, Aston HM, Malpe MS, Schulz C.   +4 more
europepmc   +1 more source

Exploring the Reproductive Toxicity of Bisphenol S Through a Network Toxicology and Molecular Docking Analysis

Pediatric Discovery, EarlyView.
Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang, Yan Fu, Xu Huang, Qitong Guo, Xiangqin Zheng, Shengde Wu, Lianju Shen, Guanghui Wei   +7 more
wiley   +1 more source

Retrotransposon activation during spermatogenesis achieves massive ecDNA biogenesis but rare integration. [PDF]

Genes Dev
Tracy L, Chen Y, Zhang ZZ.
europepmc   +1 more source