Results 191 to 200 of about 324,207 (307)

ER‐Localized Deadenylase PNLDC1 Suppresses Colorectal Cancer Progression by Targeting the mRNA Decay of TUBB4B

open access: yesExploration, EarlyView.
The deficiency of PNLDC1 exacerbates the advancement of CRC. PNLDC1 interacts with TUBB4B mRNA to regulate the p53–p21–CDK2–cyclin E2 pathway, thereby influencing the G2/M phase of the cell cycle. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related mortality, highlighting the urgent need for novel therapeutic strategies.
Lexin Liu   +18 more
wiley   +1 more source

Ionotropic glutamate receptor expression and function in the <i>Drosophila</i> testis stem cell niche. [PDF]

open access: yesMicroPubl Biol
Viveiros J   +6 more
europepmc   +1 more source

Protective Effects of Fenugreek and Stevia Extracts on Dexamethasone‐Induced Testicular Damage in a Rat Model

open access: yesFood Safety and Health, EarlyView.
Fenugreek and stevia extracts protect against dexamethasone‐induced testicular damage in male rats by enhancing antioxidant defenses, improving sperm quality, and restoring hormonal balance, highlighting their potential as natural therapeutics for preventing corticosteroid‐induced reproductive toxicity.
Mosab Gad   +3 more
wiley   +1 more source

Ubc9 Mediates SUMO2/3 Modification to Regulate Meiosis in Male Mice. [PDF]

open access: yesBiomedicines
Lv P   +6 more
europepmc   +1 more source

A rare case of perineal neuralgia treated with ultrasound‐guided nerve block combined with water separation

open access: yesIbrain, Volume 11, Issue 1, Page 106-111, Spring 2025.
A middle‐aged man presented with a right indirect inguinal hernia in November 2020 and underwent laparoscopic high ligation of the right hernial sac. Intermittent acupuncture‐like pain in the skin of the right scrotum and medial thigh occurred 1 month after surgery and lasted for 6 months. Under ultrasound guidance, ilioinguinal nerve and genitofemoral
Yong Wang   +4 more
wiley   +1 more source

Comparison of Relapse Risk Prediction Models During Active Surveillance in Stage I Seminoma: A Retrospective Multicenter Cohort Study

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT To improve the prediction of relapse for clinical stage I seminoma, we aimed to validate the Boormans model (incorporating tumor size, rete testis invasion, and lymphovascular invasion) against the conventional classification (tumor size > 4 cm/rete testis invasion).
Andreas Banner   +15 more
wiley   +1 more source

M349: Testes and epididymis

open access: yes
Clinical history : A 30 year old male with a swelling in one of the testes which was diagnosed as tubercular of the epididymis.Both the testis and epididymis was surgically removed.Diagnosis: Embryo carcinoma of the testes with infiltration of the ...

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