Results 101 to 110 of about 52,439 (348)

Noncoder : a web interface for exon array-based detection of long non-coding RNAs [PDF]

, 2012
Due to recent technical developments, a high number of long non-coding RNAs (lncRNAs) have been discovered in mammals. Although it has been shown that lncRNAs are regulated differently among tissues and disease statuses, functions of these transcripts ...
Braun, Thomas, Gellert, Pascal, Ponomareva, Yuliya, Uchida, Shizuka   +3 more
core   +1 more source

Combined Long‐Read Genome and Transcriptome Sequencing Establishes Novel Variants in MEGF8 as the Cause for Carpenter Syndrome Type 2

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Carpenter syndrome type 2 (CRPT2) is a rare autosomal recessive disease mainly characterized by craniosynostosis and polysyndactyly. CRPT2 is the rarer subtype of Carpenter syndrome (CRPTS) and is caused by biallelic variants in the multiple epidermal growth factor‐like domains 8 gene (MEGF8).
Kiana Rashidi, Bhavi P. Modi, Phillip A. Richmond, Massimo Mangino, Loryn Byres, Cassie McDonald, Joshua Dalmann, Simran Samra, Kate L. Del Bel, Anna Lehman, Jessica L. Zambonin, Stuart E. Turvey   +11 more
wiley   +1 more source

МОНГОЛ ҮҮЛДРИЙН АЗАРГАНЫ ТӨМСӨГНИЙ МОРФО-ГИСТОЛОГИЙН СУДАЛГААНЫ ЗАРИМ ҮР ДҮН

Proceedings of the Mongolian Academy of Sciences, 2016
The present study aimed to investigate correlation between testicle and body weights, cross section of seminiferous tubule and relationship between the Sertoli cells and matured sperms in stallion of Mongolian breed.
Г Бадамханд, Д Самданжамц   +1 more
doaj   +1 more source

L'Expressió al testicle de la proteïna transportadora d'esteroides sexuals humana (SHBG) té lloc a les cèl·lules germinals i no a les cèl·lules de Sertoli [PDF]

, 2007
El gen de la proteïna transportadora d'esteroides sexuals humana (hSHBG) conté dues unitats de transcripció diferents. Una d'aquestes unitats de transcripció fa aproximadament 4,3 kb, i codifica un precursor polipeptídic que és processat i secretat pels ...
Hammond, G. L., Martínez Selva, David
core  

Spectrum of Congenital Anomalies in Myhre Syndrome—Insights Into Effects Brought by Altered TGF‐β Signaling via Gain‐of‐Function Variants in SMAD4

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is a rare genetic disorder characterized by progressive multisystem involvement. Gain‐of‐function missense heterozygous variants affecting the Ile500 residue and Arg496 residue of the SMAD4 gene are implicated in this condition.
Kawmadi Gunawardena, Alessandro De Falco, Deborah Osio, Eleanor Sherlock, Emma Kivuva, Erina Sasaki, Francis H. Sansbury, Nayana Lahiri, Patricia Foley, Sahar Mansour, Shane McKee, Tazeen Ashraf, Nicola Brunetti‐Pierri, Usha Kini   +13 more
wiley   +1 more source

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

Animal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang, Keru Li, Lei Tan, Wei Chen, Shan Gao, Chenyang Liu, Shuo Pan, Jiayue He, Ning Liu, Gefan Wan, Wei Dong, Weining Kong, Bin Shen, Xiaolong Qi, Yuanwu Ma   +14 more
wiley   +1 more source

Analisis Ketahanan Hidup Tumor Testis Sel Germinal di RS Sardjito Periode 2007-2013

Indonesian Journal of Cancer, 2016
Objective: To know survival of germ cell testicle tumor at Sardjito hospital who had chemotherapy or radiotherapy and its factor which influenced their survival Method: From year 2007 until 2013, we collected patients with germ cell testicle tumor at ...
Denny Achmad Prayoga, HR Danarto
doaj   +1 more source

Reproductive anatomy and physiology of the bull (1990) [PDF]

, 1990
"Good reproductive performance of a bull is necessary to obtain a high percent calf crop when natural service is used for breeding. A bull must be fertile, capable and willing to mate a large number of cows during a short breeding season for optimum ...
Whittier, Jack
core  

A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis

Animal Models and Experimental Medicine, EarlyView.
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu, Yafei Yang, Chunxi Liu, Danting Wen, Tingyu Zhao, Ping Xie, Jing Xiao   +6 more
wiley   +1 more source

Histopathological analysis of the reproductive system of male dogs experimentally infected with Toxoplasma gondii Análise histopatológica do sistema reprodutor de cães machos experimentalmente infectados com Toxoplasma gondii

Ciência Rural, 2009
The present research aimed to describe possible histopathological alterations in the reproductive system (testicles and epididymis) of male dogs experimentally infected with Toxoplasma gondii. Canines (n=10) serologically negative for T.
Tiago Pereira Arantes, Welber Daniel Zanetti Lopes, Roberta Machado Ferreira, Juliana de Souza Pinto Pieroni, Vanessa Marigo Rocha Pinto, Thaís Rabelo dos Santos, Claúdio Alessandro Sakamoto, Alvimar José da Costa   +7 more
doaj