Results 111 to 120 of about 20,397 (261)

Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis

open access: yesAnimal Research and One Health, EarlyView.
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li   +10 more
wiley   +1 more source

Original paper
Estimation of testis volume in patients with varicocele treated by laparoscopic operation

open access: yesArchives of Medical Science, 2005
Introduction: Seminal cord varices cause degenerative processes in testicles described as “orchidopathia e varicocele”. One of the coefficients of surgical treatment efficacy could be an increase of the testicle volume after surgical procedure.
Zbigniew Jabłonowski   +2 more
doaj  

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang   +16 more
wiley   +1 more source

Pedagogical introductions to sex and gender diversity in anatomy: Exploring student perspectives

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Anatomical education has historically relied on binary terminology, reinforcing the conflation of sex, gender, and gender identity through long‐standing social and linguistic norms. To better include gender and sex diverse students and to respect the delineations between gender and sex, educators are incorporating diversity into their courses ...
Charlie W. Brake, Charys M. Martin
wiley   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub   +3 more
wiley   +1 more source

Adult Scrotal Multiparametric US – Tips and Tricks

open access: yesJournal of the Belgian Society of Radiology, 2019
Thierry Puttemans
doaj   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

open access: yesBiological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater   +12 more
wiley   +1 more source

Evidence for adaptive explanations of semelparity in animals

open access: yesBiological Reviews, EarlyView.
ABSTRACT Semelparity, the reproductive strategy of reproducing once, is widespread but uncommon in animals. Classes of models to explain the evolution of semelparity are based either on age structure and mortality schedules – demographic models in which high post‐reproductive mortality risk favours high reproductive effort and semelparity results from ...
Diana O. Fisher   +1 more
wiley   +1 more source

Choroidal metastasis of testicular choriocarcinoma: a case report and meta-analysis. [PDF]

open access: yesAm J Ophthalmol Case Rep
Moudgil A   +4 more
europepmc   +1 more source

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