Results 91 to 100 of about 4,783,149 (369)
ChemMedChem, EarlyView.Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto +12 more
wiley +1 more source
Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis
Clinical Pharmacology &Therapeutics, EarlyView.Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic +4 more
wiley +1 more source
Compound Nevus with Severe Dysplastic Feature in Mixed Germ Cell Tumor: A Case Report
Translational Research in Urology, 2020 Introduction Testicular cancer is the most common tumor of the genital tract of 18-39 years-old men; its incidence is increasing in recent decades. However, the 10-year survival rate of testicular cancer is above 90%, which can result from radiation and
Alimohammad Fakhr Yasseri +3 more
doaj +1 more source
PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. [PDF]
, 2018 Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Chen, Di +4 more
core +2 more sources
Testicular cancer from diagnosis to epigenetic factors
OncoTarget, 2017 Testicular cancer (TC) is one of the most common neoplasms that occurs in male and includes germ cell tumors (GCT), sex cord-gonadal stromal tumors and secondary testicular tumors.
M. Boccellino +18 more
semanticscholar +1 more source
Diagnostic Cytopathology, EarlyView.ABSTRACT Malignant mesothelioma (MM) is a rare yet aggressive neoplasm that arises from mesothelial cells lining the thoracic and abdominal cavities, the pericardium, and the tunica testis. Characterized by rapid progression, high invasiveness, and a poor prognosis, MM poses significant clinical challenges. SMARCB1, also referred to as INI‐1, hSNF5, or
Jun Yang +4 more
wiley +1 more source
Online Journal of Health & Allied Sciences, 2020 Objective: The study was conducted to assess the level of awareness about testicular cancer and the prevalence of the practice of testicular self-examination (TSE) in the Indian expatriates in the Middle East and thereby propose appropriate ...
Sajad Ahmad Salati
doaj
A multi-exon deletion within WWOX is associated with a 46,XY disorder of sex development [PDF]
, 2011 Disorders of sex development (DSD) are congenital conditions where chromosomal, gonad or genital development is atypical. In a significant proportion of 46,XY DSD cases it is not possible to identify a causative mutation, making genetic counseling ...
AJ Notini +32 more
core +1 more source
Environmental and Molecular Mutagenesis, EarlyView.Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons +17 more
wiley +1 more source
Does ochratoxin A (OTA) cause testicular cancer in humans?
Acta Medica Lituanica, 2011 Ochratoxin A (OTA) is a naturally occurring contaminant of cereals, pigmeat, and other foods and is a known genotoxic in animals. It is a nephrotoxin and a carcinogen associated with Balkan endemic nephropathy and urinary tract tumours.
Jayachandra SRINIVASA
doaj +1 more source