Results 101 to 110 of about 3,327,559 (283)

Human Umbilical Cord Mesenchymal Stem Cell–Derived Exosomes Attenuate Renal Fibrosis by Suppressing Fibroblast Activation via the INHBA/PI3K/AKT Pathway

open access: yesPediatric Discovery, EarlyView.
MSC‐Exo derived from human umbilical cord (HucMSC‐Exo) downregulates INHBA expression, consequently modulating the PI3K/AKT signaling cascade. This regulation attenuates renal fibroblast activation and extracellular matrix deposition, thereby exerting a renoprotective effect against fibrosis.
Meiling Chen   +11 more
wiley   +1 more source

Asynchronous Bilateral Testicular Cancer in A Patient with Bilateral Undescended Testicle: A Case Report

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2021
BACKGROUND AND OBJECTIVE: Testicular cancer is almost the only common genitourinary tract cancer at a young age. One of the risk factors for testicular tumors is undescended testicles.
H Shafi   +3 more
doaj  

MicroRNA‐130a‐3p Targets the Androgen‐Related Transcription Factor MAFB: Effects on Proliferation, Migration, Apoptosis, and Cell Cycle in Hypospadias

open access: yesPediatric Discovery, EarlyView.
MicroRNA‐130a‐3p targets and inhibits MAFB expression, leading to the development of hypospadimas. MicroRNA‐130a‐3p inhibits the expression of MAFB, disrupts the normal processes of cell proliferation, migration, cell apoptosis, and cycle progression, and ultimately leads to the development of hypospadias.
Jiaxin Zhou   +10 more
wiley   +1 more source

Mortality and incidence of second cancers following treatment for testicular cancer. [PDF]

open access: yes, 2007
We studied 5555 seminoma patients and 3733 patients with nonseminomatous testicular cancers diagnosed in Southeast England between 1960 and 2004. For both groups survival improved over time: 10-year relative survival increased from 78% in 1960-1969 to 99%
Møller, H   +6 more
core   +1 more source

Characteristics, properties and limitations of per‐ or polyfluoroalkyl substances (PFASs) and fluoropolymers

open access: yesPolymer International, EarlyView.
An overview and categorization of man‐made per‐ or polyfluoroalkyl substances (PFASs) including low‐molar‐mass and high‐molar‐mass fluorochemicals, and their international regulations is presented. Though certain PFASs are toxic, bioaccumulative and cross the human cellular membranes, others, such as fluoropolymers, are safe, reliable and involved in ...
Bruno Améduri
wiley   +1 more source

Association between low total serum testosterone and body mass index in Australian survivors of testicular cancer: a retrospective analysis

open access: yesBasic and Clinical Andrology
Background Primary hypogonadism is a recognised complication in survivors of testicular cancer. However, secondary hypogonadism can result from other causes that suppress the hypothalamic-pituitary axis, including obesity, high dose glucocorticoids ...
Grace Y. Kim   +11 more
doaj   +1 more source

Nivel de conocimiento del riesgo de cáncer testicular en hombres jóvenes

open access: yesRevista Finlay, 2023
Fundamento: el cáncer de testículo es la neoplasia maligna más común en hombres jóvenes y la detección temprana mediante la autoexploración testicular es fundamental.
María Fernanda Cueva Moncayo   +2 more
doaj  

Testicular microlithiasis: Case report and literature review

open access: yesAfrican Journal of Urology, 2012
We present an interesting case of bilateral microlithiasis. Microlithiasis is usually considered a benign condition with no need for follow-up. However, when a patient with testicular microlithiasis has a positive family history of testicular cancer ...
W. Akhter   +4 more
doaj   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

open access: yesPrecision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang   +7 more
wiley   +1 more source

Plasma Steroid Trajectories From Day‐of‐Surgery Baseline After Robot‐Assisted Radical Prostatectomy for Prostate Cancer

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Circulating steroid trajectories after robot‐assisted radical prostatectomy are poorly characterized from the day‐of‐surgery baseline, and relevant biology extends beyond testosterone and dihydrotestosterone to adrenal‐derived 11‐oxygenated androgens and steroid conjugate turnover.
Jiri Heracek   +8 more
wiley   +1 more source

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