Results 121 to 130 of about 3,327,559 (283)

Late orchiopexy in boys with cryptorchidism and increased risk of testicular cancer [PDF]

, 2018
La criptorquidia se define como la falta de descenso a la porción inferior del escroto de uno o ambos testículos. Constituye el trastorno endocrinológico más frecuente en el varón y puede formar parte de enfermedades sindrómicas diversas o presentarse de
Díaz, Yenifer, Castro, Sebastián, Rey, Rodolfo Alberto   +2 more
core   +1 more source

Burden of testicular, paratesticular and extragonadal germ cell tumours in Europe

, 2012
We provide updated estimates of survival, incidence, complete prevalence, and proportion cured for patients with testicular/paratesticular and extragonadal germ cell cancers in Europe, grouped according to the new list of cancer types developed by ...
Berrino, F., Ardanaz, E., Mallone, S., Necchi, A, Trama, A, Ardanaz, E, Schaapveld, M, A. Znaor, J. Gietema, Gietema, J., Schaapveld, M., F. Berrino, A. Necchi, RARECARE Working group, Znaor, A., N. Nicolai, Nicolai, N, Berrino, F, S. Mallone, Mallone, S, Necchi, A., Nicolai, N., E. Ardanaz, Znaor, A, M. Schaapveld, Gietema, J, Trama, A., A. Trama   +27 more
core   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

Andrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann, Johanna Hochmuth‐Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Marta Godlewska, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf   +9 more
wiley   +1 more source

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

Andrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby, Sylvianne Hennebicq, Jacqueline Saias, Florence Brugnon, Isabelle Berthaut, Myriam Daudin, Louis Bujan, Ludovic Dumont, Christine Rondanino, Aurélie Feraille, Nathalie Rives   +10 more
wiley   +1 more source

Epstein-barr virus and cytomegalovirus in relation to testicular-cancer risk:A nested case-control study

, 1999
An infectious etiology of testicular cancer has been suggested. We have evaluated seroreactivity against cytomegalovirus (CMV) and Epstein-Barr virus (EBV) in relation to testicular-cancer risk in a case-control study, nested within a cohort of ...
Tretli, Steinar, Adami, Hans-Olov, Andersen, Aage, Lipworth, Loren, Melbye, Mads, Ekbom, Anders, Adami, Hans Olov, Linde, Annika, Engstrand, Lars, Akre, Olof, Andersen, Aaage   +10 more
core   +1 more source

Cryopreservation of Spermatozoa Prior and Post‐Orchiectomy in Patients With Testicular Germ Cell Cancer—Does the Timing Matter?

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell cancer (TGCC) is the most frequent malignancy in young men of reproductive age. According to guidelines, semen cryopreservation should be performed prior to orchiectomy. Lack of time and local facilities as well as mental pressure are challenges in terms of fertility preservation before surgery.
Yuhe Tang, Gerald Pühse, Sabine Kliesch, Jann‐Frederik Cremers, Maria Schubert   +4 more
wiley   +1 more source

Inhibition of HMGA2 Leads to Reduced Cell Proliferation and Increased Apoptosis in Human Embryonal Carcinoma Cell Lines

Andrology, EarlyView.
ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino, Matteo Lampitto, Alfredo Fusco, Marco Barchi, Francesco Esposito, Paolo Chieffi   +5 more
wiley   +1 more source

An interview study of men discovering testicular cancer

, 2000
Testicular cancer affects men between 15 and 45 years old. The aim of this study was to show how men with testicular cancer discover their cancer, react to physical changes, and take action.
Eriksson, Charli,, Sandén, Inger,, Sätterlund Larsson, Ullabeth,   +2 more
core  

A Unified Machine Learning Model for Relapse Prediction in Clinical Stage I Testicular Cancer

Andrology, EarlyView.
ABSTRACT Background Approximately one‐fourth of patients with clinical stage I testicular cancer relapse. For decades, risk stratification has been based on different tumor characteristics for seminomas and non‐seminomas. Previous studies primarily used Cox proportional‐hazards models and included only a limited number of variables.
Thomas Wagner, Ramtin Zargari Marandi, Jakob Lauritsen, Daniel Dawson Murray, Mikkel Bandak, Birgitte Grønkær Toft, Dan Berney, Gedske Daugaard   +7 more
wiley   +1 more source