Results 141 to 150 of about 64,337 (253)

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

The FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari, Budheswar Dehury, Rounak Roy, Radhakrishnan Periyasamy, Indrashis Bhattacharya, Mahesh Sahare, Srinivasan Vijayraghavan, Souvik Dey   +7 more
wiley   +1 more source

Biochemical profiling and symptomatology of androgen deficiency in males with cluster headache: A prospective case–control study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Cluster headache (CH) has historically been considered a male‐dominated disorder, suggesting a role for androgens in its pathophysiology. We aimed to evaluate hormone profiles and symptoms of androgen deficiency in CH.
Willemijn C. Naber, Roemer B. Brandt, Mariël Leon Morales‐Grooters, Ronald van der Wal, Sjoerd A. A. van den Berg, Jelle J. Goeman, Antoinette Maassen van den Brink, Rolf Fronczek   +7 more
wiley   +1 more source

Microsurgical Onco-Testicular Sperm Extraction in a Patient With Testicular Cancer and Congenital Unilateral Testicular Absence: A Case Report. [PDF]

IJU Case Rep
Matsumoto Y, Amano T, Hachiya M, Fujita T, Imao T.   +4 more
europepmc   +1 more source

Pattern‐based interpretation of SOX2 expression in ovarian teratomas: avoiding diagnostic pitfalls in the distinction between immature and mature neuroectodermal elements

Histopathology, EarlyView.
Ovarian immature teratoma grading may be confounded by mature neuroectodermal mimics. SOX2 labelled immature neuroepithelium but also mature ependymal and glial tissue, while SALL4 was negative in mature mimics and variably expressed in immature neuroepithelium.
Agnese Orsatti, Caterina Ravaioli, Marco Grillini, Eugenia Franchini, João Lobo, Andres M. Acosta, Veronica Mollica, Claudio Zamagni, Pierandrea De Iaco, Anna Myriam Perrone, Michelangelo Fiorentino, Giovanni Tallini, W. Glenn McCluggage, Costantino Ricci, Antonio De Leo   +14 more
wiley   +1 more source

Trends and projections of global testicular cancer burden from 1990 to 2035. [PDF]

Front Oncol
Mao C, Tao C, Yang C, Shen J, Li G.
europepmc   +1 more source

Critical Windows of Air Pollution Exposure During Spermatogenesis and Intrauterine Insemination Outcomes

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Male preconception health remains a critically under‐addressed area of family planning. While research suggests air pollution may harm semen quality, downstream impacts on pregnancy, particularly for more vulnerable infertility treatment populations, are understudied.
Lindsey M. Russo, J. Richard Pilsner, Timothy P. Canty, Neil J. Perkins, Pauline Mendola, Karen C. Schliep, May Shaaban, Rachael B. Hemmert, Akanksha Singh, Allison M. Ring, James A. Vanderslice, C. Matthew Peterson, Erica B. Johnstone, Kaniz Rabeya, Carrie Nobles   +14 more
wiley   +1 more source

Potential profile analysis of reproductive concerns and influencing factors among testicular cancer patients of reproductive age. [PDF]

BMC Cancer
Hu Y, Chen G, Dong Y, Li X, Fu C, Hu W, Fu X.   +6 more
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Sperm banking in testicular cancer survivors Low utilization, high costs, and patient-reported barriers from a Canadian cohort. [PDF]

Can Urol Assoc J
Lu S, Ko Y, Fathy M, Patel P.
europepmc   +1 more source

Phthalates measured at birth and risk of testicular cancer in adolescents and young adults. [PDF]

JNCI Cancer Spectr
Metayer C, Gennings C, Morimoto LM, Mistry S, McGlynn KA, Dolios G, Guan H, Gonzaga R C, Andra SS, Petrick L.   +9 more
europepmc   +1 more source