Results 171 to 180 of about 3,327,559 (283)

The Need for a Global Registry for Charting the Natural History of Klinefelter Syndrome

open access: yesAndrology, EarlyView.
ABSTRACT Background Although Klinefelter Syndrome (KS) represents the most common sex chromosome aneuploidy, several gaps in knowledge persist regarding optimal management of individuals with this condition. Individuals with KS can have a diverse phenotype including endocrine, neurodevelopmental, and cardiovascular manifestations.
Malika Alimussina   +13 more
wiley   +1 more source

Screening of adolescents for testicular cancer-a nationwide retrospective cohort study. [PDF]

open access: yesAm J Epidemiol
Zloof Y   +10 more
europepmc   +1 more source

Differential Sperm DNA Methylation Profiles in Healthy Men With High Versus Low Adherence to the Mediterranean Diet in the Led‐Fertyl Study

open access: yesAndrology, EarlyView.
ABSTRACT Background Diet is known to play an essential role not only in sperm quality but also in offspring health, likely mediated through the sperm epigenome. Moreover, one of the main components of the Mediterranean diet (MedDiet) (i.e., nuts) have shown to impact sperm DNA methylation patterns.
Rashmi Agarwal   +10 more
wiley   +1 more source

Difficult Conversation Case: Missed Testicular Cancer. [PDF]

open access: yesJ Educ Teach Emerg Med
Ginsburg J   +4 more
europepmc   +1 more source

Androgens Modulate Tumor–Immune Interactions in Testicular Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Background The majority of testicular germ cell tumors (TGCT) are derived from the germ cell neoplasia in situ and arise after puberty in the local presence of high levels of testosterone. The seminoma subtype features a rich inflammatory infiltrate which impacts tumor progression but the role of testosterone in shaping tumor–immune ...
Ida Hamann   +6 more
wiley   +1 more source

The effect of time to nephrectomy on cancer‐specific mortality in pathological T stage (pT)1b–2 renal cancer

open access: yesBJU International, EarlyView.
Objective To assess the impact of prolonged time to surgery on cancer‐specific mortality (CSM) in patients with pathological T stage (pT)1b–2 N0M0 renal cell carcinoma (RCC) treated with nephrectomy (either partial [PN] or radical [RN]). Within the Surveillance, Epidemiology and End Results (SEER) database (2004–2021), we tested the effect of time to ...
Michele Nicolazzini   +17 more
wiley   +1 more source

SLAMF6 Enhances the Efficacy of Anti‐PD‐L1 Immunotherapy in CRC Through the STAT1/CXCL10 Signaling Axis

open access: yesCancer Science, EarlyView.
SLAMF6 recruits SHP‐2 to activate STAT1, upregulates CXCL10 and PD‐L1, promotes CD8+T cell infiltration, and enhances the efficacy of anti‐PD‐L1 therapy. ABSTRACT As a T‐cell receptor co‐stimulatory protein, signaling lymphocyte activation molecule family 6 (SLAMF6) is a member of the immune cell activating receptor family and is expressed on T cells ...
Yu Wu   +8 more
wiley   +1 more source

Anxiety, Depression, and Suicidality Among Testicular Cancer Survivors. [PDF]

open access: yesCancer Med
Meagher M   +17 more
europepmc   +1 more source

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