Testicular Cancer-Associated Paraneoplastic Neurologic Syndromes.
Harahsheh E +9 more
europepmc +1 more source
Etoposide dosing challenges in a testicular cancer patient with hepatic impairment and drug-drug interactions-a case report. [PDF]
Op 't Hoog CJP +5 more
europepmc +1 more source
AC591 and its core active component 18β‐glycyrrhetinic acid effectively alleviate cisplatin‐induced ototoxicity by binding p53 and suppressing p53‐mediated ferroptosis, representing promising agents for preventing cisplatin‐related hearing loss. ABSTRACT Cisplatin is a widely utilized chemotherapeutic agent for the treatment of malignant cancers ...
Yunhao Wu +9 more
wiley +1 more source
Prognostic Nomograms and Scoring System: Novel Approaches to Forecast Overall Survival and Cancer-Specific Survival in Patients With Testicular Cancer. [PDF]
Huang X +5 more
europepmc +1 more source
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu +8 more
wiley +1 more source
Testicular cancer: a bibliometric review of the Middle East and North African region. [PDF]
Nasrallah OG +8 more
europepmc +1 more source
Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor +6 more
wiley +1 more source
Reassessing pre-existing comorbidity patterns in testicular cancer: controversies and future directions. [PDF]
Chen Y, Liu Y, Liu C.
europepmc +1 more source
Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan +10 more
wiley +1 more source
Testicular Biopsies in Adolescent and Adult Andrological Patients: The EAA Clinical Guidelines
ABSTRACT Background Histological evaluation of testicular tissue is central to the assessment of infertile men, particularly those at an increased risk of testicular germ cell tumors (TGCT). Traditionally, testicular biopsies have been used primarily for diagnostic purposes, such as the detection of germ cell neoplasia in situ (GCNIS). With advances in
Lise Aksglaede +11 more
wiley +1 more source

