Results 211 to 220 of about 51,434 (299)

Predicting orchiectomy in testicular torsion using hybrid machine learning and explainable AI: a web-based clinical decision support system. [PDF]

World J Urol
Çift A, Kutlu H, Çoban F, Sulhan H, Sever S, Koç MK, Kılınç M, Kalyenci B.   +7 more
europepmc   +1 more source

Spontaneous miscarriage after intracytoplasmic sperm injection with frozen sperm of patients with testicular germ cell tumour

BJU International, EarlyView.
Objective To clarify the impact of chromosomal aberrations on the offspring of patients with testicular germ cell tumour (TGCT) by evaluating the outcomes of intracytoplasmic sperm injection (ICSI). Patients and Methods Under the ethical review of Yokohama City University, 12 patients with TGCT and 25 with non‐TGCT cancer who had cryopreserved sperm ...
Haru Hamada, Akifumi Ijuin, Tomonari Hayama, Naoki Tsuchiya, Sumiko Sueyoshi, Misaki Toda, Ai Miyakoshi, Mayuko Kurumizaka, Marina Saito, Yuki Oike, Hiroe Ueno, Shinnosuke Kuroda, Kazumi Takeshima, Teppei Takeshima, Shin Saito, Ryoko Asano, Taichi Mizushima, Yasushi Yumura, Hideya Sakakibara, Etsuko Miyagi, Miki Tanoshima, Mariko Murase   +21 more
wiley   +1 more source

Giant seminoma of the testis (2.51 kg) in a setting of severe occupational and lifestyle exposures: a case report and pathophysiological insights. [PDF]

Front Med (Lausanne)
Tao HP, Chen B, Chen YR, Yang G, Mao KL.
europepmc   +1 more source

MTAP Deficiency as a Metabolic Vulnerability in Cancer: Implications for Synthetic Lethal Therapy

Cancer Science, EarlyView.
MTAP deletion creates a therapeutically actionable metabolic vulnerability through MTA accumulation and PRMT5 dependency. This review summarizes the biochemical basis of MTAP‐directed synthetic lethality, emerging PRMT5/MAT2A inhibitors, clinicogenomic features of MTAP‐deleted tumors, and future strategies for precision oncology.
Hiroaki Ikushima, Hidenori Kage
wiley   +1 more source

A sound approach to stay on the ball-a review of scrotal pathologies on ultrasound imaging. [PDF]

Br J Radiol
Lam Shin Cheung J, Bhaduri M.
europepmc   +1 more source

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

Clinical Endocrinology, EarlyView.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu, Yue Li, Meng Sun, Yulin Li, Panpan Li, Hui Zou   +5 more
wiley   +1 more source

Pubertal Dynamics of Sertoli and Leydig Cell Dysfunction in Klinefelter Syndrome

Clinical Endocrinology, EarlyView.
ABSTRACT Context Klinefelter syndrome (KS), defined by a 47, XXY karyotype, is commonly associated with progressive testicular failure. The precise timing of Sertoli and Leydig cell dysfunction during puberty remains unclear. Objective To determine the onset and progression of testicular insufficiency during puberty in KS, and to assess whether ...
Tredez Axelle, Christine Lefevre, Simon Boussion, Cindy Colson, Iva Gueorguieva, Francois Marcelli, Anne Laure Barbotin, Pascal Pigny, Hamza Benderradji, Clara Leroy   +9 more
wiley   +1 more source

Testicular shear wave elastography in varicocele: measurement strategy and clinical application. [PDF]

Basic Clin Androl
Zhang L, Li Y, Zhang L, Liang Y, Zhuo Y, Huang J.   +5 more
europepmc   +1 more source

Service Evaluation: Increasing Transparency in Decision‐Making and Acknowledging Professional's Feelings When Working With Gender Dysphoria in Children's Mental Health Services

Child &Family Social Work, EarlyView.
ABSTRACT There is a lack of evidence‐based guidelines for supporting young people with gender dysphoria and intellectual disability in the United Kingdom. The NHS is moving towards more care being provided by non‐specialist gender services and it is unclear what this may feel like for professionals in these services.
Laura Prodger, Alex Zouloumis, Melanie Hodgkinson, Laura Bartlett   +3 more
wiley   +1 more source

Preventive Strategies and Biomarkers in Male Reproductive Health from Multidisciplinary Perspective: Narrative Review. [PDF]

Medicina (Kaunas)
Ispossunova G, Nikolic D, Alchinbayev M, Nurbakyt A, Aitmanbetova A, Bizic M, Lackovic M, Milanovic F, Amangeldi A, Ispossunova A, Kuzmanovic Pficer J.   +10 more
europepmc   +1 more source