Results 191 to 200 of about 2,277,679 (245)
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Impact of thyroid disease on testicular function
Endocrine, 2017Testis was considered unresponsive to thyroid hormone for a long time. However, like in animals, the presence of thyroid hormone receptors in different testicular cell types was demonstrated also in humans. Accordingly, thyrotoxicosis and hypothyroidism have remarkable effects on testicular function and more extensively on fertility.Thyrotoxicosis and ...
LA VIGNERA, SANDRO SALVUCCIO MARIA +6 more
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Testicular dysfunction in untreated Hodgkin's disease
The American Journal of Medicine, 1982Gonadal function was examined in 19 young men with Hodgkin's disease before therapy and compared with that of 11 men with other malignancies, 13 men with primary testicular failure, and 19 normal men of similar age. Total (p less than 0.01) and free (p less than 0.05) testosterone levels were decreased in Hodgkin's disease.
R A, Vigersky +3 more
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Role of testicular autoantigens and influence of lymphokines in testicular autoimmune disease
Journal of Reproductive Immunology, 1990The present data on testicular autoimmune disease suggest that CD4+ helper type T cells are responsible for adoptive transfer of murine experimental autoimmune orchitis (EAO). In passive EAO, the earliest lymphoid cell infiltration is confined to terminal segments of seminiferous tubules. Both orchitis and vasitis develop.
T D, Yule, C A, Mahi-Brown, K S, Tung
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Testicular Dysfunction in Systemic Diseases
Endocrinology and Metabolism Clinics of North America, 1994The testis is the most accessible endocrine organ to clinical examination and is highly responsive to environmental factors, including systemic illness. The clinical management of any disorder warrants consideration of the effects of illness and its treatment of male reproductive function.
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Testicular and epididymal involvement in Fabry's disease
The Journal of Pathology, 1983AbstractAutopsy specimens of the testes and epididymis of a 32‐year‐old male with Fabry's disease were studied by light and electron microscopy. The characteristic ceramide deposits (lamellar inclusions, myeloid‐bodies, zebra‐bodies) were found in the Leydig cells as well as in the epithelial lining of both the ductuli efferentes and the ductus of the ...
M, Nistal, R, Paniagua, M L, Picazo
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Testicular vasculitis: Implications for systemic disease
Human Pathology, 1988Nine cases of testicular vasculitis were identified from the surgical pathology and autopsy files of the Johns Hopkins Hospital. In three cases this was the initial manifestation of polyarteritis nodosa. Two of these men presented with recurrent testicular pain and fever, with orchiectomy samples showing focal infarcts and necrotizing vasculitis.
M S, Shurbaji, J I, Epstein
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Renal and Testicular Agenesis in a Patient With Darier’s Disease
Journal of Urology, 1985Darier's disease is a familial disorder of the skin that has been associated with corneal, bone, pulmonary, and urogenital abnormalities. This report describes a novel urogenital anomaly, namely renal and testicular agenesis, in a patient with Darier's disease.
L Y, Matsuoka +2 more
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Testicular macrophages: development and function in health and disease
Trends in Immunology, 2022Macrophages comprise a heterogeneous immune cell population and display niche-specific phenotypes and functions in almost all organs. Testicular macrophages (TMs) perform essential immune and non-immune functions in the mammalian male gonads. Here, we discuss the most recent findings on TM ontogeny, heterogeneity, and function under steady state and ...
Meinhardt, A. +2 more
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Testicular tumor concomitant with von Recklinghausen's disease
Medical and Pediatric Oncology, 1988AbstractNeurofibromatosis or Von Recklinghausen's disease is an autosomal dominant disorder, associated with an excess of malignant tumors. The most common neurofibromatosis‐associated malignancies are derived from neurogenic tissues, although several malignancies that did not originate from neurogenic tissue are also described. This paper provides the
J J, Groot-Loonen +2 more
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Testicular lesions in Whipple's disease.
The Journal of laboratory and clinical medicine, 1985In two patients with Whipple's disease a variety of abnormalities were found in the testis. In both there was a thickened tunica albuginea containing macrophages filled with Schiff-positive bacilli, and both exhibited Whipple bacilli alone or in small clumps within the tunica media of the testicular arteries.
T N, James +3 more
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