ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec +18 more
wiley +1 more source
Diagnostic value of systemic immune-inflammation index in differentiating testicular torsion from epididymo-orchitis based on symptom duration: A retrospective observational study. [PDF]
Demir M +5 more
europepmc +1 more source
Nut Consumption and Sperm Quality in Healthy Men: Results From the Led‐Fertyl Study
ABSTRACT Background Nuts are rich in antioxidants and other bioactive compounds, and recent evidence suggests that their regular consumption may be associated with sperm quality. However, the current scientific evidence remains limited and inconsistent.
Estefanía Dávila‐Córdova +10 more
wiley +1 more source
Preserving Fertility After Bilateral Testicular Gunshot Injury: A Case Report. [PDF]
Sholan R, Aliyev R, Karimov S.
europepmc +1 more source
ABSTRACT Background Testicular germ cell tumours (TGCTs) are the most common type of tumour diagnosed in young men, and reliable non‐invasive biomarkers are crucial for clinical management. MicroRNAs (miRNAs) from the miR‐371–373 cluster have recently been identified as novel and more sensitive serum biomarkers than the conventional protein‐based ...
Nina Mørup +7 more
wiley +1 more source
Rescue of ICSI failure in non-obstructive azoospermia by switching from cryopreserved to fresh testicular sperm: a paired clinical analysis. [PDF]
Zhang L +5 more
europepmc +1 more source
Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan +10 more
wiley +1 more source
Febuxostat alleviates testicular dysfunction induced by cyclophosphamide in rats via modulation of pyroptosis and mTOR autophagy axis. [PDF]
Atia HA +6 more
europepmc +1 more source
Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice
ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda +2 more
wiley +1 more source

