Results 81 to 90 of about 51,434 (299)

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

open access: yesAnimal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen   +2 more
wiley   +1 more source

Clinical evaluation of pediatric testicular masses

open access: yesUrology Research and Practice, 2019
Scrotal pathologies are frequently seen in pediatric population. There are plenty of diseases that can be seen with similar clinical findings. These are generally benign lesions that can be diagnosed by simple physical examination and radiological ...
Cenk Murat Yazıcı   +2 more
doaj   +2 more sources

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang   +16 more
wiley   +1 more source

Modern competency‐based teaching of human sexual development

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler   +2 more
wiley   +1 more source

Testicular alterations in hansen's disease

open access: yesHansenologia Internationalis: hanseníase e outras doenças infecciosas, 1991
Fifty testicular specimens and seminal fluid of 10 normal individuals and 24 patients with Hansen's disease were studied. General and early histological alterations, the frequency of young spermatides in tubular lumen and the measure of the diameters of 1.450 seminiferous tubules were checked.
H.O. ARRUDA, A.P. CEDENHO, L.H.F. ARRUDA
openaire   +2 more sources

Clinical evaluation of pediatric testicular masses

open access: yes, 2010
Scrotal pathologies are frequently seen in pediatric population. There are plenty of diseases that can be seen with similar clinical findings. These are generally benign lesions that can be diagnosed by simple physical examination and radiological ...
Cenk Murat Yazici   +5 more
core   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

open access: yesBiological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater   +12 more
wiley   +1 more source

Role of Lipoic Acid in Testosterone Production in Males

open access: yesThe World Journal of Men's Health
Testosterone extends its impact beyond sexual function, playing a crucial role in shaping overall male health, including aspects such as muscle mass, bone density, mood regulation, and energy levels.
Saleem Ali Banihani
doaj   +1 more source

Preserved Spermatogenesis and Hormonal Function in Men Receiving a Pretomanid Regimen (BPaMZ) for Pulmonary Drug‐Resistant Tuberculosis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pretomanid is a component of the World Health Organization‐recommended treatment regimen for drug‐resistant tuberculosis in patients aged ≥ 14 years. While preclinical rodent studies identified testicular toxicity as a potential clinical liability at elevated doses, no corresponding effects were observed in nonhuman primates nor clinical hormone ...
Pauline Howell   +13 more
wiley   +1 more source

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