Results 61 to 70 of about 2,277,679 (245)

Enhancing Men's Awareness of Testicular Diseases (E-MAT) using virtual reality: A randomised pilot feasibility study and mixed method process evaluation.

PLoS ONE
IntroductionTesticular cancer is among the most common malignancies in men under the age of 50 years. Most testicular symptoms are linked to benign diseases. Men's awareness of testicular diseases and testicular self-examination behaviours are suboptimal.
Mohamad M Saab, Megan McCarthy, Martin P Davoren, Frances Shiely, Janas M Harrington, Gillian W Shorter, David Murphy, Billy O'Mahony, Eoghan Cooke, Aileen Murphy, Ann Kirby, Michael J Rovito, Steve Robertson, Serena FitzGerald, Alan O'Connor, Mícheál O'Riordan, Josephine Hegarty, Darren Dahly   +17 more
doaj   +1 more source

Loss of Nuclear Functions of HOXA10 Is Associated With Testicular Cancer Proliferation

Frontiers in Oncology, 2018
Background: HOXA10 is a key transcriptional factor that regulates testis development as reported from previous transgenic mouse models and human inherited diseases. However, whether it also plays important roles in promoting the development of testicular
Ruiqi Chen, Ruiqi Chen, Haolong Li, Yinan Li, Ladan Fazli, Martin Gleave, Lucia Nappi, Xuesen Dong   +7 more
doaj   +1 more source

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

Advanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang, Xinyuan Li, Lixia Huang, Xiangcai Zhang, Wujian Ke   +4 more
wiley   +1 more source

College Men's Knowledge, Attitudes, and Beliefs About Testicular Cancer

American Journal of Men's Health, 2007
There is a paucity of information about what college-age men know about testicular cancer, making targeted educational programs difficult. The most common age group affected by testicular cancer is 15- to 40-yearolds.
Christine Makosky Daley PhD, MA, SM
doaj   +1 more source

Primary Testicular B-cell Lymphoma

, 2015
Primary testicular lymphoma constitutes only 1-7% of all testicular neoplasms and less than 1% of all non-Hodgkin lymphoma. We report a 69-year-old man who presented with a painful right testicular mass. Treatment modalities consist of surgical excision,
Musa Ekici, Aykut Buğra Şentürk, Hamit Ersoy   +2 more
core   +1 more source

Macrophage GLUD1 is Essential for Redox Balance and Immune Homeostasis in Cardiac Injury

Advanced Science, EarlyView.
Excessive free radical production and dysregulated immune responses are key contributors to myocardial ischemia‐reperfusion (IR) injury. Macrophage GLUD1 activity safeguards against HIF‐1α accumulation and maladaptive responses to IR‐induced ROS production.
Tingting Jin, Chaojie Lai, Qingyan Zhou, Ruilin Wang, Yiping Tong, Wentao Chen, Nikola Rabrenovic, Tingyu Zhang, Xinrong Ren, Chengchen Huang, Jiawen Chen, Ran Li, Luyang Yu, Massimiliano Mazzone, Wenbin Zhang, Guosheng Fu, Min Shang   +16 more
wiley   +1 more source

Clinical evaluation of pediatric testicular masses

Urology Research and Practice, 2019
Scrotal pathologies are frequently seen in pediatric population. There are plenty of diseases that can be seen with similar clinical findings. These are generally benign lesions that can be diagnosed by simple physical examination and radiological ...
Cenk Murat Yazıcı, Polat Türker, Selçuk Yücel   +2 more
doaj   +2 more sources

Primary Testicular Lymphoma: A Case Report

, 2015
Primary testicular lymphoma is a rarely seen testicular tumor accounting for 1-9% of all testicular tumors. The dominant histological subtype is diffuse large B-cell lymphoma. It is the most common testicular malignancy in men aged over 60 years.
Emrah Okulu, Huban Sibel Orhun, Fatih Akdemir, Önder Kayıgil, Okulu, EMRAH, KAYIGİL, ÖNDER, Akdemir, Fatih, Orhun, Huban Sibel   +7 more
core   +1 more source

Single‐Cell Insights Into Pathogenic Profile of Orchitis and SREBP2‐Associated Cholesterol Dysregulation in Spermatogenic Failure

Advanced Science, EarlyView.
A first single‐cell atlas of human orchitis reveals coordinated germ‐cell loss, somatic niche dysfunction, and immune‐metabolic remodeling. Aberrant SREBP2 activation in testicular somatic cells emerges as a central pathogenic node, while Fatostatin‐mediated inhibition of the SREBP pathway improves spermatogenesis, fibrosis, and lipid accumulation in a
Yanlin Tang, Qiaoling Jiang, Yuwen Liu, Wenxiu Zhang, Lina Cui, Xiaojian Lu, Ziyan Zhuang, Jianxing Cheng, Songzhan Gao, Yangyi Fang, Kai Hong, Jie Qiao, Xiaoyan Wang, Hui Jiang, Zhe Zhang, Jingtao Guo, Qiang Liu   +16 more
wiley   +1 more source

Transcriptional Profiling of Luteinizing Hormone Receptor-Deficient Mice Before and after Testosterone Treatment Provides Insight into the Hormonal Control of Postnatal Testicular Development and Leydig Cell Differentiation [PDF]

, 2010
Luteinizing hormone (LH) is a key regulator of male fertility through its effects on testosterone secretion by Leydig cells. Transcriptional control of this is, however, currently poorly understood.
Affara, Nabeel, Abel, M, Ellis, Peter J.I., Dunmore, B., Bauer, Johann W., Griffin, Darren K.   +5 more
core   +1 more source